Novel Type of Streptococcus pneumoniae Causing Multidrug-Resistant Acute Otitis Media in Children

Xu, Qingfu; Pichichero, Michael E.; Casey, Janet R.; Zeng, Mingtao

Back to Previous Page

Novel Type of Streptococcus pneumoniae Causing Multidrug-Resistant Acute Otitis Media in Children

Published Date:

Apr 2009

Source:

Emerg Infect Dis. 15(4):547-551.

Language:

English

[PDF-209.94 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Xu, Qingfu ; Pichichero, Michael E. ; Casey, Janet R. ; Zeng, Mingtao ;

Description:

After our recent discovery of a Streptococcus pneumoniae 19A "superbug" (Legacy strain) that is resistant to all Food and Drug Administration-approved antimicrobial drugs for treatment of acute otitis media (AOM) in children, other S. pneumoniae isolates from children with AOM were characterized by multilocus sequence typing (MLST). Among 40 isolates studied, 16 (40%) were serotype 19A, and 9 (23%) were resistant to multiple antimicrobial drugs. Two others had unreported sequence types (STs) that expressed the 19A capsule, and 8 (88%) of the 9 multidrug-resistant strains were serotype 19A, including the Legacy strain with the new ST-2722. In genetic relatedness, ST-2722 belonged to a cluster of reported strains of S. pneumoniae in which all strains had 6 of the same alleles as ST-156. The multidrug-resistant strains related to ST-156 expressed different capsular serotypes: 9V, 14, 11A, 15C, and 19F.

Subject:

[+]

Document Type:

Journal Article

Place as Subject:

New York

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

File Type:

Supporting Files:

	license.txt	text/plain
	07-1704-F1.gif	image/gif
	07-1704-F1.jpg	image/jpeg
	07-1704-F2.gif	image/gif
	07-1704-F2.jpg	image/jpeg
	07-1704-F3.gif	image/gif
	07-1704-F3.jpg	image/jpeg
	07-1704_finalR.nxml	text/plain

No Related Documents.

Increase in Pilus Islet 2–encoded Pili among Streptococcus pneumoniae Isolates, Atlanta, Georgia, USA

[PDF - 258.34 KB]

Personal Author:

Zähner, Dorothea ; Gudlavalleti, Aditya ; ...

Published Date:

Jun 2010

Source:

Emerg Infect Dis. 16(6):955-962.

Description:

To define the prevalence of pilus islet 2 (PI-2)-encoded pili in Streptococcus pneumoniae in a geographically defined area, we examined 590 S. pneumon...

File Type:

[PDF - 258.34 KB]

File Type:

[PDF - 258.34 KB]
High Prevalence of Spirochetosis in Cholera Patients, Bangladesh

[PDF - 197.48 KB]

Personal Author:

Nelson, Eric J. ; Tanudra, Angela ; ...

Published Date:

Apr 2009

Source:

Emerg Infect Dis. 15(4):571-573.

Description:

The microbes that accompany the etiologic agent of cholera, Vibrio cholerae, are only now being defined. In this study, spirochetes from the genus Bra...

File Type:

[PDF - 197.48 KB]

File Type:

[PDF - 197.48 KB]
Worldwide Diversity of Klebsiella pneumoniae That Produce β-Lactamase blaKPC-2 Gene1

[PDF - 379.30 KB]

Personal Author:

Cuzon, Gaëlle ; Naas, Thierry ; ...

Published Date:

Sep 2010

Source:

Emerg Infect Dis. 16(9):1349-1356.

Description:

Klebsiella pneumoniaeisolates that produce carbapenemases (KPCs) are rapidly disseminating worldwide. To determine their genetic background, we invest...

File Type:

[PDF - 379.30 KB]

File Type:

[PDF - 379.30 KB]
Fluoroquinolone Resistance in Penicillin-resistant Streptococcus pneumoniae Clones, Spain

[PDF - 203.05 KB]

Personal Author:

de la Campa, Adela G. ; Balsalobre, Luz ; ...

Corporate Authors:

Spanish Pneumococcal Infection Study Network G03/103

Published Date:

Oct 2004

Source:

Emerg Infect Dis. 10(10):1751-1759.

Description:

Among 2,882 Streptococcus pneumoniae sent to the Spanish Reference Laboratory during 2002, 75 (2.6%) were ciprofloxacin-resistant. Resistance was asso...

File Type:

[PDF - 203.05 KB]

File Type:

[PDF - 203.05 KB]
Characterization of Full Genome of Rat Hepatitis E Virus Strain from Vietnam

[PDF - 1.04 MB]

Personal Author:

Li, Tian-Cheng ; Ami, Yasushi ; ...

Published Date:

Jan 2013

Source:

Emerg Infect Dis. 19(1):115-118.

Description:

We amplified the complete genome of the rat hepatitis E virus (HEV) Vietnam strain (V-105) and analyzed the nucleotide and amino acid sequences. The e...

File Type:

[PDF - 1.04 MB]

File Type:

[PDF - 1.04 MB]

Novel Type of Streptococcus pneumoniae Causing Multidrug-Resistant Acute Otitis Media in Children

Novel Type of Streptococcus pneumoniae Causing Multidrug-Resistant Acute Otitis Media in Children

You May Also Like:

Have Questions?

CDC INFORMATION

CONNECT WITH CDC