Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Lewis, Hannah C. ; Mølbak, Kåre ; Reese, Catrin ; Aarestrup, Frank M. ; Selchau, Mette ; ... More +
Lewis, Hannah C. ; Mølbak, Kåre ; Reese, Catrin ; Aarestrup, Frank M. ; Selchau, Mette ; Sørum, Marit ; Skov, Robert L. Less -
Description:
An emerging subtype of methicillin-resistant Staphylococcus aureus (MRSA), clonal complex (CC) 398, is associated with animals, particularly pigs. We conducted a matched case-control and a case-case study comparing 21 CC398 case-patients with 2 controls randomly selected from the Danish Civil Registry and 2 case-patients infected with MRSA other than CC398. On farms of case-patients, animals were examined for MRSA. Thirteen case-patients reported pig exposure. Living or working on farms with animals was an independent risk factor for CC398 in the case-control (matched odds ratio [MOR] 35.4, 95% confidence interval [CI] 2.7-469.8) and the case-case study (MOR 14.5, 95%CI 2.7-76.7). History of hospitalization was associated with an increased risk only in the case-control study (MOR 11.4, 95% CI 1.4-94.8). A total of 23 of 50 pigs on 4 of 5 farms were positive for CC398. Our results, corroborated by microbiologic testing, demonstrate that pigs are a source of CC398 in Denmark.
Subject:
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Animals
Case-control Studies
CC398
Community-acquired Infections
Denmark
Disease Reservoirs
Domestic Swine (pig)
Environmental Exposure
Epidemiology
Humans
Methicillin Resistance
Multivariate Analysis
Research
Staphylococcal Infections
Staphylococcus Aureus
Swine
Animals
Case-Control Studies
Methicillin Resistance
Research

Source:
Emerg Infect Dis. 14(9):1383-1389
Pubmed ID:
18760004
Pubmed Central ID:
PMC2603104
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:9f3dd2be86dbb389b982011dce605232f4c65a1fe00ff998a8c95f9bbd030cd5
File Type:

Supporting Files

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