Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Aichelburg, Alexander C. ; Walochnik, Julia ; Assadian, Ojan ; Prosch, Helmut ; Steuer, Andrea ; Perneczky, Gedeon ; Visvesvara, Govinda S. ; Aspöck, Horst ; Vetter, Norbert
• Description:
  We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation.
• Subjects:
  • Dispatch
  • Acanthamoeba
  • granulomatous Acanthamoeba encephalitis (GAE)
  • tuberculosis
  • immunocompromised non–HIV-infected patient
  • miltefosine
  • dispatch
  • Administration, Oral
  • Administration, Topical
  • Adult
  More +
• Source:
  Emerg Infect Dis. 14(11):1743-1746
• Pubmed ID:
  18976559
• Pubmed Central ID:
  PMC2630722
• Document Type:
  Journal Article
• Volume:
  14
• Issue:
  11
• Download URL:
  https://stacks.cdc.gov/view/cdc/16932/cdc_16932_DS1.pdf
• File Type:
  [PDF - 300.53 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:629ce0affe26ddc5e825ffbce65a90ac05482c8c5e9426ec6ab247df37915f6c