Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Aichelburg, Alexander C. ; Walochnik, Julia ; Assadian, Ojan ; Prosch, Helmut ; Steuer, Andrea ; Perneczky, Gedeon ; Visvesvara, Govinda S. ; Aspöck, Horst ; Vetter, Norbert
• Description:
  We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation.
• Subjects:
  Acanthamoeba Administration, Oral Administration, Topical Adult Amebiasis Animals Antiprotozoal Agents Dispatch Encephalitis Granuloma Granulomatous Acanthamoeba Encephalitis (GAE) Humans Immunocompromised Host Immunocompromised Non–HIV-infected Patient Male Miltefosine Phosphorylcholine Skin Ulcer Treatment Outcome Tuberculosis Tuberculosis, Miliary

  More +
• Source:
  Emerg Infect Dis. 14(11):1743-1746
• Pubmed ID:
  18976559
• Pubmed Central ID:
  PMC2630722
• Document Type:
  Journal Article
• Volume:
  14
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:629ce0affe26ddc5e825ffbce65a90ac05482c8c5e9426ec6ab247df37915f6c
• Download URL:
  https://stacks.cdc.gov/view/cdc/16932/cdc_16932_DS1.pdf
• File Type:
  [PDF - 300.53 KB ]