Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

Aichelburg, Alexander C.; Walochnik, Julia; Assadian, Ojan; Prosch, Helmut; Steuer, Andrea; Perneczky, Gedeon; Visvesvara, Govinda S.; Aspöck, Horst; Vetter, Norbert

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine

Nov 2008
By Aichelburg, Alexander C. ; Walochnik, Julia ; Assadian, Ojan ; ...
Source: Emerg Infect Dis. 14(11):1743-1746

[PDF-300.53 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Aichelburg, Alexander C. ; Walochnik, Julia ; Assadian, Ojan ; Prosch, Helmut ; Steuer, Andrea ; ... More +

Aichelburg, Alexander C. ; Walochnik, Julia ; Assadian, Ojan ; Prosch, Helmut ; Steuer, Andrea ; Perneczky, Gedeon ; Visvesvara, Govinda S. ; Aspöck, Horst ; Vetter, Norbert Less -
Description:

We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no signs of infection 2 years after treatment cessation.
Subjects:

[+]

Acanthamoeba Administration, Oral Administration, Topical Adult Amebiasis Animals Antiprotozoal Agents Dispatch Encephalitis Granuloma Granulomatous Acanthamoeba Encephalitis (GAE) Humans Immunocompromised Host Immunocompromised Non–HIV-infected Patient Male Miltefosine Phosphorylcholine Skin Ulcer Treatment Outcome Tuberculosis Tuberculosis, Miliary
Source:

Emerg Infect Dis. 14(11):1743-1746
Pubmed ID:

18976559
Pubmed Central ID:

PMC2630722
Document Type:

Journal Article
Volume:

14
Issue:

11
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:629ce0affe26ddc5e825ffbce65a90ac05482c8c5e9426ec6ab247df37915f6c
Download URL:

https://stacks.cdc.gov/view/cdc/16932/cdc_16932_DS1.pdf
File Type:

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