Super-Sentinel Chickens and Detection of Low-Pathogenicity Influenza Virus

Marcus, Philip I.; Girshick, Theodore; van der Heide, Louis; Sekellick, Margaret J.

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Super-Sentinel Chickens and Detection of Low-Pathogenicity Influenza Virus

Oct 2007
By Marcus, Philip I. ; Girshick, Theodore ; van der Heide, Louis ; ...
Source: Emerg Infect Dis. 13(10):1608-1610.

[PDF-212.32 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Marcus, Philip I. ; Girshick, Theodore ; van der Heide, Louis ; Sekellick, Margaret J.

Marcus, Philip I. ; Girshick, Theodore ; van der Heide, Louis ; Sekellick, Margaret J. Less -
Description:

Chicken interferon-alpha administered perorally in drinking water acts on the oropharyngeal mucosal system as an adjuvant that causes chickens to rapidly seroconvert after natural infection by low-pathogenicity Influenza virus. These chickens, termed super sentinels, can serve as sensitive early detectors of clinically inapparent infections.
Subjects:

[+]

Adjuvants, Immunologic Administration, Oral Animals Avian Influenza Chicken Interferon Chickens Dispatch Immunocompromised Host Influenza A Virus, H7N7 Subtype Influenza In Birds Influenza Virus Interferon Type I Peroral Adjuvant Recombinant Proteins Sentinel Chickens Sentinel Surveillance Seroepidemiologic Studies
Source:

Emerg Infect Dis. 13(10):1608-1610.
Document Type:

Journal Article
Volume:

13
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:56918ad2b656c7469fca25cccf72f5506f1010671a5e78ebd608249cd31f87ca
Download URL:

https://stacks.cdc.gov/view/cdc/16649/cdc_16649_DS1.pdf
File Type:

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