Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Fischer, Thea Kølsen ; Nielsen, Nete Munk ; Wohlfahrt, Jan ; Pærregaard, Anders ;
Fischer, Thea Kølsen ; Nielsen, Nete Munk ; Wohlfahrt, Jan ; Pærregaard, Anders ; Less -
Description:
In anticipation of licensure and introduction of rotavirus vaccine into the western market, we used modeling of national hospital registry data to determine the incidence and direct medical costs of annual rotavirus-associated admissions over >11 years in Denmark. Diarrhea-associated hospitalizations coded as nonspecified viral or presumed infectious have demonstrated a marked winter peak similar to that of rotavirus-associated hospitalizations, which suggests that the registered rotavirus-coded admissions are grossly underestimated. We therefore obtained more realistic estimates by 2 different models, which indicated 2.4 and 2.5 (for children <5 years of age) and 4.9 and 5.3 (for children <2 years of age) rotavirus-associated admissions per 1,000 children per year, respectively. These admissions amount to associated direct medical costs of US $1.7-1.8 million per year. Using 2 simple models to analyze readily available hospital discharge data resulted in more consistent and reliable estimates.
Subject:
[+]
Child, Preschool
Children
Denmark
Diarrhea
Economic Burden
Epidemiology
Health Care Costs
Hospitalization
Humans
Incidence
Infant
Models, Theoretical
Registries
Research
Rotavirus
Rotavirus Infections
Seasons
Statistics As Topic
Vaccination
Research

Source:
Emerg Infect Dis. 13(6):855-859. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:072cfc892b2b1dfcab200ea9effacdf836a605bc18c0d8e9ebfc57b10fe4e48e
File Type:

Supporting Files

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