Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Levy, Isaac ; Grisaru-Soen, Galia ; Lerner-Geva, Liat ; Kerem, Eitan ; Blau, Hana ; ... More +
Levy, Isaac ; Grisaru-Soen, Galia ; Lerner-Geva, Liat ; Kerem, Eitan ; Blau, Hana ; Bentur, Lea ; Aviram, Micha ; Rivlin, Joseph ; Picard, Elie ; Lavy, Anita ; Yahav, Yakov ; Rahav, Galia Less -
Description:
This 2-year cross-sectional evaluation of nontuberculous mycobacterial (NTM) infections involved all Israeli medical centers that treat cystic fibrosis patients. The study comprised 186 patients whose sputum was analyzed for NTM. The prevalence of NTM isolates was 22.6%, and 6.5% and 10.8% of the patients fulfilled the 1997 and 2007 American Thoracic Society criteria for NTM lung disease, respectively. Mycobacterium simiae (40.5%), M. abscessus (31.0%), and M. avium complex (14.3%) were the most prevalent. Presence of Aspergillus spp. in sputum and the number of sputum specimens processed for mycobacteria were the most significant predictors for isolation of NTM (odds ratio [OR] = 5.14, 95% confidence interval [CI] 1.87-14.11 and OR = 1.47, 95% CI 1.17-1.85, respectively). The incidence of NTM pulmonary infections is increasing among cystic fibrosis patients, reflecting the increase in longevity of such patients as well as environmental exposure to various species of mycobacteria.
Subject:
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Adolescent Adult Case-Control Studies Child Cross-Sectional Studies Cystic Fibrosis Female Humans Israel Male Mycobacterium Abscessus Mycobacterium Infections Mycobacterium Simiae Nontuberculous Mycobacteria Research Retrospective Studies
Source:
Emerg Infect Dis. 14(3):378-384.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:b1c9b469079bf5ecccf9d5e51aaa07d3495cd36f3ad61ea5bc75265a84fe0441
Download URL:
https://stacks.cdc.gov/view/cdc/16613/cdc_16613_DS1.pdf
File Type:

Supporting Files

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