Outbreak of Buruli Ulcer, Southeastern Australia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Johnson, Paul D.R. ; Azuolas, Joseph ; Lavender, Caroline J. ; Wishart, Elwyn ; Stinear, Timothy P. ; Hayman, John A. ; Brown, Lynne ; Jenkin, Grant A. ; Fyfe, Janet A.M.
• Description:
  Buruli ulcer (BU) occurs in >30 countries. The causative organism, Mycobacterium ulcerans, is acquired from the environment, but the exact mode of transmission is unknown. We investigated an outbreak of BU in a small coastal town in southeastern Australia and screened by PCR mosquitoes caught there. All cases of BU were confirmed by culture or PCR. Mosquitoes were trapped in multiple locations during a 26-month period. BU developed in 48 residents of Point Lonsdale/Queenscliff and 31 visitors from January 2001 through April 2007. We tested 11,504 mosquitoes trapped at Point Lonsdale (predominantly Aedes camptorhynchus). Forty-eight pools (5 species) were positive for insertion sequence IS2404 (maximum likelihood estimate 4.3/1,000), and we confirmed the presence of M. ulcerans in a subset of pools by detection of 3 additional PCR targets.
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Animals Buruli Ulcer Child Child, Preschool Communicable Diseases, Emerging Culicidae Disease Outbreaks Environmental Microbiology Female Humans Infant Insect Vectors Male Middle Aged Polymerase Chain Reaction

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• Source:
  Emerg Infect Dis. 13(11):1653-1660.
• Document Type:
  Journal Article
• Place as Subject:
  Australia
• Volume:
  13
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6ad0b29f232dfeebe49a9d7fb530ece211e4ce301d092c36ebcc60900f0ba91a
• Download URL:
  https://stacks.cdc.gov/view/cdc/16603/cdc_16603_DS1.pdf
• File Type:
  [PDF - 494.04 KB ]