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Fatal Disseminated Acanthamoeba lenticulata Acanthamebiasis in a Heart Transplant Patient
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  1. Acanthamoeba Endophthalmitis During Treatment for Cutaneous Disease in a Renal Transplant Patient
    Personal Author:
    Kutner, Allison; Aldrich, Margaret; Patel, Sarju; Kang, Joann J.; Amin, Bijal; Mann, Ranon; Ali, Ibne Karim M.; Martines, Roosecelis Brasil; Cope, Jennifer Rittenhouse; De Boccardo, Graciela O.; Puius, Yoram A.;
    Published Date:
    February 12 2018
    Source:
    Transpl Infect Dis. 20(2):e12843
    Description:
    Acanthamoeba infections are difficult to diagnose and treat. We present a renal transplant patient who developed Acanthamoeba endophthalmitis on therapy with posaconazole and miltefosine for cutaneous acanthamobiasis. The patient was maintained on in...
    File Type:
    Filetype[PDF - 347.36 KB]
  2. Successful Treatment of Disseminated Acanthamoeba sp. Infection with Miltefosine
    Personal Author:
    Aichelburg, Alexander C.; Walochnik, Julia; Assadian, Ojan; Prosch, Helmut; Steuer, Andrea; Perneczky, Gedeon; Visvesvara, Govinda S.; Aspöck, Horst; Vetter, Norbert;
    Published Date:
    Nov 2008
    Source:
    Emerg Infect Dis. 14(11):1743-1746
    Description:
    We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with milte...
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    Filetype[PDF - 300.53 KB]
  3. Disseminated Acanthamoeba infection in a heart transplant recipient treated successfully with a miltefosine-containing regimen: case report and review of the literature
    Personal Author:
    Brondfield, MN; Reid, MR; Rutishauser, RL; Cope, JR; Tang, J; Ritter, JM; Matanock, A; Ali, I; Doernberg, SB; Hilts-Horeczko, A; DeMarco, T; Klein, L; Babik, JM;
    Published Date:
    Mar 06 2017
    Source:
    Transpl Infect Dis. 19(2).
    Description:
    Disseminated acanthamoebiasis is a rare, often fatal, infection most commonly affecting immunocompromised patients. We report a case involving sinuses, skin, and bone in a 60-year-old woman 5 months after heart transplantation. She improved with a c...
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  4. Characterization of a New Pathogenic Acanthamoeba Species, A. byersi n. sp., Isolated from a Human with Fatal Amoebic Encephalitis
    Personal Author:
    Qvarnstrom, Yvonne; Nerad, Thomas A.; Visvesvara, Govinda S.;
    Published Date:
    2013 Nov-Dec
    Source:
    J Eukaryot Microbiol. 60(6):626-633.
    Description:
    Acanthamoeba spp. are free-living amoebae that are ubiquitous in natural environments. They can cause cutaneous, nasopharyngeal, and disseminated infection, leading to granulomatous amebic encephalitis (GAE) in immunocompromised individuals. In addit...
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  5. Yersinia pestis Survival and Replication in Potential Ameba Reservoir
    Personal Author:
    Markman, David W.; Antolin, Michael F.; Bowen, Richard A.; Wheat, William H.; Woods, Michael; Gonzalez-Juarrero, Mercedes; Jackson, Mary;
    Published Date:
    Feb 2018
    Source:
    Emerg Infect Dis. 24(2):294-302.
    Description:
    Plague ecology is characterized by sporadic epizootics, then periods of dormancy. Building evidence suggests environmentally ubiquitous amebae act as feral macrophages and hosts to many intracellular pathogens. We conducted environmental genetic surv...
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    Filetype[PDF - 2.08 MB]