Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Buckeridge, David L. ; Owens, Douglas K. ; Switzer, Paul ; Frank, John ; Musen, Mark A.
Buckeridge, David L. ; Owens, Douglas K. ; Switzer, Paul ; Frank, John ; Musen, Mark A. Less -
Description:
Timely detection of an inhalational anthrax outbreak is critical for clinical and public health management. Syndromic surveillance has received considerable investment, but little is known about how it will perform relative to routine clinical case finding for detection of an inhalational anthrax outbreak. We conducted a simulation study to compare clinical case finding with syndromic surveillance for detection of an outbreak of inhalational anthrax. After simulated release of 1 kg of anthrax spores, the proportion of outbreaks detected first by syndromic surveillance was 0.59 at a specificity of 0.9 and 0.28 at a specificity of 0.975. The mean detection benefit of syndromic surveillance was 1.0 day at a specificity of 0.9 and 0.32 days at a specificity of 0.975. When syndromic surveillance was sufficiently sensitive to detect a substantial proportion of outbreaks before clinical case finding, it generated frequent false alarms.
Subject:
[+]
Anthrax
Bacillus Anthracis
Bioterrorism
Computer Simulation
Delivery Of Health Care
Disease Outbreaks
Evaluation
Humans
Inhalation Exposure
Markov Chains
Models, Biological
Outbreak Detection
Population Surveillance
Research
Sensitivity And Specificity
Simulation
Syndromic Surveillance

Source:
Emerg Infect Dis. 12(12):1942-1949.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:8c8feca151b8706308937e3d22df45e562389a5501d62e86d7812cdce2c80c26
File Type:

Supporting Files

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