Aedes aegypti Larval Indices and Risk for Dengue Epidemics

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Sanchez, Lizet ; Vanlerberghe, Veerle ; Alfonso, Lázara ; Marquetti, María del Carmen ; Guzman, María Guadalupe ; Bisset, Juan ; van der Stuyft, Patrick
• Description:
  We assessed in a case-control study the test-validity of Aedes larval indices for the 2000 Havana outbreak. "Cases" were blocks where a dengue fever patient lived during the outbreak. "Controls" were randomly sampled blocks. Before, during, and after the epidemic, we calculated Breteau index (BI) and house index at the area, neighborhood, and block level. We constructed receiver operating characteristic (ROC) curves to determine their performance as predictors of dengue transmission. We observed a pronounced effect of the level of measurement. The BI(max) (maximum block BI in a radius of 100 m) at 2-month intervals had an area under the ROC curve of 71%. At a cutoff of 4.0, it significantly (odds ratio 6.00, p<0.05) predicted transmission with 78% sensitivity and 63% specificity. Analysis of BI at the local level, with human-defined boundaries, could be introduced in control programs to identify neighborhoods at high risk for dengue transmission.
• Subjects:
  Aedes Animals Area Under Curve Case-Control Studies Dengue Dengue Virus Disease Outbreaks Humans Insect Vectors Larva Predictive Value Of Tests Risk Factors Roc Curve Sensitivity And Specificity

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• Source:
  Emerg Infect Dis. 12(5):800-806.
• Document Type:
  Journal Article
• Place as Subject:
  Cuba
• Volume:
  12
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6a015bcf7335dbf1b45aa6592483eb796398652ffdf68747add5d3bff67d345d
• Download URL:
  https://stacks.cdc.gov/view/cdc/16009/cdc_16009_DS1.pdf
• File Type:
  [PDF - 353.99 KB ]