Isolate Removal Methods and Methicillin-resistant Staphylococcus aureus Surveillance
Published Date:Oct 2005
Source:Emerg Infect Dis. 11(10):1552-1557.
Antimicrobial Drug Resistance
Intensive Care Units
Methicillin-resistant Staphylococcus Aureus
Microbial Sensitivity Tests
Funding:U50/CCU 923810-01/CC/ODCDC CDC HHS/United States
Description:The effect of duplicate isolate removal strategies on Staphylococcal aureus susceptibility to oxacillin was compared by using antimicrobial test results for 14,595 isolates from statewide surveillance in Hawaii in 2002. No removal was compared to most resistant and most susceptible methods at 365 days and to the National Committee for Clinical Laboratory Standards (NCCLS) and Cerner algorithms at 3-, 10-, 30-, 90-, and 365-day analysis periods. Overall, no removal produced the lowest estimates of susceptibility. Estimates with either NCCLS or Cerner differed by <2% when the analysis period was the same; with either method, the difference observed between a 90- and a 365-day period was <1%. The effect of duplicate isolate removal was greater for inpatient than outpatient settings. Considering the ease of implementation and comparability of results, we recommend using the first isolate of a given species per patient to calculate susceptibility frequencies for S. aureus to oxacillin.
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