Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Burrough, Eric R. ; Magstadt, Drew R. ; Petersen, Barbara ; Timmermans, Simon J. ; Gauger, Phillip C. ; Zhang, Jianqiang ; Siepker, Chris ; Mainenti, Marta ; Li, Ganwu ; Thompson, Alexis C. ; Gorden, Patrick J. ; Plummer, Paul J. ; Main, Rodger
  More +
• Description:
  We report highly pathogenic avian influenza A(H5N1) virus in dairy cattle and cats in Kansas and Texas, United States, which reflects the continued spread of clade 2.3.4.4b viruses that entered the country in late 2021. Infected cattle experienced nonspecific illness, reduced feed intake and rumination, and an abrupt drop in milk production, but fatal systemic influenza infection developed in domestic cats fed raw (unpasteurized) colostrum and milk from affected cows. Cow-to-cow transmission appears to have occurred because infections were observed in cattle on Michigan, Idaho, and Ohio farms where avian influenza virus-infected cows were transported. Although the US Food and Drug Administration has indicated the commercial milk supply remains safe, the detection of influenza virus in unpasteurized bovine milk is a concern because of potential cross-species transmission. Continued surveillance of highly pathogenic avian influenza viruses in domestic production animals is needed to prevent cross-species and mammal-to-mammal transmission.
• Subjects:
  • Expedited
  • Research
  • Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024
  • Animals
  • Cats
  • Cattle
  • Cat Diseases
  • Cattle Diseases
  • Orthomyxoviridae Infections
  • Influenza A Virus, H5N1 Subtype
  More +
• Keywords:
  • influenza
  • highly pathogenic avian influenza A(H5N1)
  • HPAI
  • avian influenza
  • H5N1
  • clade 2.3.4.4b
  • bovine influenza A
  • dairy cattle
  • cats
  • spillover
  More +
• Source:
  Emerg Infect Dis. 2024; 30(7):1335-1343
• Pubmed ID:
  38683888
• Pubmed Central ID:
  PMC11210653
• Document Type:
  Journal Article
• Volume:
  30
• Issue:
  7
• Download URL:
  https://stacks.cdc.gov/view/cdc/158121/cdc_158121_DS1.pdf
• File Type:
  [PDF - 4.02 MB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:0b591a8666ecd7ad69d54a3ef9ad0a76373763685d76e4847d121a855e21e0e83dca3d375ec4470e19b95ec52d634d555354764cc61fc950cef85f537e17b4c4