Evidence of Orientia spp. Endemicity among Severe Infectious Disease Cohorts, Uganda

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Blair, Paul W. ; Kobba, Kenneth ; Okello, Stephen ; Alharthi, Sultanah ; Naluyima, Prossy ; Clemens, Emily ; Kibuuka, Hannah ; Clark, Danielle V. ; Kakooza, Francis ; Lamorde, Mohammed ; Manabe, Yukari C. ; Dumler, J. Stephen ; Illness, Acute Febrile
• Corporate Authors:
  Sepsis in Uganda study teams
• Description:
  At 3 severe infection cohort sites in Uganda, Orientia seropositivity was common. We identified 4 seroconversion cases and 1 PCR-positive case. These results provide serologic and molecular support for Orientia spp. circulating in sub-Saharan Africa, possibly expanding its endemic range. Orientia infections could cause severe illness and hospitalizations in this region.
• Subjects:
  Adolescent Adult Cohort Studies Endemic Diseases Female Humans Male Middle Aged Young Adult
• Keywords:
  Acute Febrile Illness Africa Bacteria Orientia Scrub Typhus Uganda Vector-borne Infections
• Source:
  Emerg Infect Dis. 2024; 30(7):1442-1446
• Pubmed ID:
  38916638
• Pubmed Central ID:
  PMC11210639
• Document Type:
  Journal Article
• Genre:
  Dispatch
• Place as Subject:
  Uganda
• Volume:
  30
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:c2e91306057a6f4f6c14d92a0737571a7ccc9ceb6acd7905d105c084cba1c083
• Download URL:
  https://stacks.cdc.gov/view/cdc/158093/cdc_158093_DS1.pdf
• File Type:
  [PDF - 1.36 MB ]