Molecular Evidence of Pneumocystis Transmission in Pediatric Transplant Unit
Published Date:Feb 2005
Source:Emerg Infect Dis. 11(2):330-332.
Disease Transmission, Infectious
DNA, Ribosomal Spacer
Pediatric Renal Transplantation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Single-strand Conformation Polymorphism
Description:We describe an outbreak of Pneumocystis jirovecii pneumonia in a pediatric renal transplant unit, likely attributable to patient-to-patient transmission. Single-strand conformation polymorphism molecular typing showed that 3 affected patients had acquired the same 2 strains of Pneumocystis, which suggests interhuman infection. An infant with mitochondriopathy was the probable index patient.
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