Hepatitis C Virus Infection, Linxian, China1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Zhang, Mingdong ; Sun, Xiu-Di ; Mark, Steven D. ; Chen, Wen ; Wong, Lara ; Dawsey, Sanford M. ; Qiao, You-Lin ; Fraumeni, Joseph F. ; Taylor, Philip R. ; O’Brien, Thomas R.
• Description:
  Bloodborne viruses may have spread in rural China during the past 25 years, but population-based prevalence estimates are lacking. We examined the frequency of hepatitis C virus (HCV) and HIV type 1 (HIV-1) among residents of Linxian, a rural community in Henan Province. In 2000, blood was collected from participants (> or = 55 years of age) who had enrolled in a population-based nutritional intervention trial in 1985. We randomly selected 500 participants for HCV testing and 200 participants for HIV-1 testing. For HCV, 48 (9.6%) of 500 participants were positive by enzyme immunoassay and recombinant immunoblot assay (95% confidence interval, 7.0%-12.2%), and prevalence was lowest in the most geographically isolated participants. Among the HCV-infected participants, 42 had a specimen available from 1985, of which 16 (38.1%) were positive for HCV. For HIV-1, 0/200 participants were positive. We conclude that HCV is now a common infection among older adults in Linxian, China.
• Subjects:
  Aged Aged, 80 And Over Communicable Diseases, Emerging Female Hepacivirus Hepatitis B Hepatitis B Surface Antigens Hepatitis C Hepatitis C Antibodies HIV-1 HIV Antibodies HIV Infections Humans Male Middle Aged Prevalence Research Rural Population Seroepidemiologic Studies

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• Source:
  Emerg Infect Dis. 11(1):17-21.
• Document Type:
  Journal Article
• Place as Subject:
  China
• Location:
  Asia
• Volume:
  11
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:36f1a9a9bc4c48fa240008ab9fba14583c57b60e452dc458095c8bff06c8684d
• Download URL:
  https://stacks.cdc.gov/view/cdc/15596/cdc_15596_DS1.pdf
• File Type:
  [PDF - 138.83 KB ]