Hepatitis C Virus Infection, Linxian, China1
Published Date:Jan 2005
Source:Emerg Infect Dis. 11(1):17-21.
Aged, 80 And Over
Communicable Diseases, Emerging
Hepatitis B Surface Antigens
Hepatitis B Virus (HBV)
Hepatitis C Antibodies
Hepatitis C Virus (HCV)
Human Immunodeficiency Virus Type 1 (HIV-1)
Description:Bloodborne viruses may have spread in rural China during the past 25 years, but population-based prevalence estimates are lacking. We examined the frequency of hepatitis C virus (HCV) and HIV type 1 (HIV-1) among residents of Linxian, a rural community in Henan Province. In 2000, blood was collected from participants (> or = 55 years of age) who had enrolled in a population-based nutritional intervention trial in 1985. We randomly selected 500 participants for HCV testing and 200 participants for HIV-1 testing. For HCV, 48 (9.6%) of 500 participants were positive by enzyme immunoassay and recombinant immunoblot assay (95% confidence interval, 7.0%-12.2%), and prevalence was lowest in the most geographically isolated participants. Among the HCV-infected participants, 42 had a specimen available from 1985, of which 16 (38.1%) were positive for HCV. For HIV-1, 0/200 participants were positive. We conclude that HCV is now a common infection among older adults in Linxian, China.
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