Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7.
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Published Date:1998 Oct-Dec
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Source:Emerg Infect Dis. 4(4):615-617.
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Description:It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecular evolution.
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