Molecular and epidemiologic analysis of dengue virus isolates from Somalia.

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Kanesa-thasan, N. ; Chang, G. J. ; Smoak, B. L. ; Magill, A. ; Burrous, M. J. ; Hoke, C. H.
• Description:
  Nucleotide sequence analysis was performed on 14 dengue virus isolates (13 dengue-2 viruses and 1 dengue-3 virus) recovered from febrile soldiers in Somalia in 1993. The dengue-2 viruses were most closely related to dengue-2 virus recovered in Somalia in 1984. However, differences in nucleotide sequence (0.35% to 1.35%) were evident among the 1993 isolates. These differences were closely associated with the geographic location of the infection as well as with different times of infection at the same location. Genetic difference between strains was not associated with differences in clinical features. Molecular analysis of dengue viruses is a useful adjunct to epidemiologic investigation of their distribution over distance and time.
• Subjects:
  Adult Base Sequence Dengue Dengue Virus Genes, Viral Humans Male Military Personnel Molecular Epidemiology Molecular Sequence Data Phylogeny Polymerase Chain Reaction Sequence Analysis, Dna

  More +
• Source:
  Emerg Infect Dis. 4(2):299-303.
• Document Type:
  Journal Article
• Place as Subject:
  Somalia
• Volume:
  4
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:82855584a118385c22b78f14a970e9f057ce1556a0ff58874a06a9890dd0b3bc
• Download URL:
  https://stacks.cdc.gov/view/cdc/15495/cdc_15495_DS1.pdf
• File Type:
  [PDF - 48.43 KB ]