Crimean-Congo Hemorrhagic Fever Virus for Clinicians—Epidemiology, Clinical Manifestations, and Prevention

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Frank, Maria G. ; Weaver, Gretchen ; Raabe, Vanessa
• Corporate Authors:
  State of the Clinical Science Working Group of the National Emerging Pathogens Training ; Education Center’s Special Pathogens Research Network2
• Description:
  Crimean-Congo hemorrhagic fever (CCHF) is a tickborne infection that can range from asymptomatic to fatal and has been described in >30 countries. Early identification and isolation of patients with suspected or confirmed CCHF and the use of appropriate prevention and control measures are essential for preventing human-to-human transmission. Here, we provide an overview of the epidemiology, clinical features, and prevention and control of CCHF. CCHF poses a continued public health threat given its wide geographic distribution, potential to spread to new regions, propensity for genetic variability, and potential for severe and fatal illness, in addition to the limited medical countermeasures for prophylaxis and treatment. A high index of suspicion, comprehensive travel and epidemiologic history, and clinical evaluation are essential for prompt diagnosis. Infection control measures can be effective in reducing the risk for transmission but require correct and consistent application.
• Subjects:
  Animals Hemorrhagic Fever, Crimean Hemorrhagic Fever Virus, Crimean-Congo Humans Ticks
• Keywords:
  Bunyavirus Countermeasure Crimean-Congo Hemorrhagic Fever Treatment Vaccine Vector-borne Infections Viral Hemorrhagic Fever Viruses
• Source:
  Emerg Infect Dis. 2024; 30(5):854-863
• Pubmed ID:
  38666548
• Pubmed Central ID:
  PMC11060446
• Document Type:
  Journal Article
• Genre:
  Synopsis
• Volume:
  30
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:d558150407dbfc16adeec33ef43698f06c46ee8e6e436360819c6f3e14c8cbd2
• Download URL:
  https://stacks.cdc.gov/view/cdc/154877/cdc_154877_DS1.pdf
• File Type:
  [PDF - 1.59 MB ]