Weight Status of Children Participating in the National Spina Bifida Patient Registry

Details

• Alternative Title:
  Pediatrics
• Personal Author:
  Polfuss, Michele ; Liu, Tiebin ; Smith, Kathryn ; Murphy, Pamela S. ; Ward, Elisabeth ; Thibadeau, Judy ; Dosa, Nienke P. ; Wang, Yinding ; Sawin, Kathleen J.
• Description:
  OBJECTIVES:
  
  Describe the distribution of weight status categories and determine factors associated with overweight and obesity (OW/OB) in children and adolescents with spina bifida (SB) using the National Spina Bifida Patient Registry.
  
  METHODS:
  
  Demographic, anthropometric, and clinical data collected from 2009 through 2018 was used to describe the prevalence of OW/OB. The generalized estimating equation model (GEE) identified factors associated with OW/OB among individuals with SB.
  
  RESULTS:
  
  Participants (n = 7215) were aged 2 to 19 years (mean = 11.1; standard error, 0.06) and 51.4% female. The majority were non-Hispanic white (57.2%) followed by Hispanic or Latino (25.1%) and non-Hispanic Black (7.5%). The myelomeningocele (MMC) subgroup accounted for 76.3%. Most (60.2%) were community ambulators. The overall percentage of OW/OB was 45.2%, with 49.2% of MMC and 32.0% of nonmyelomeningocele OW/OB. Following the Centers for Disease Control Obesity Severity Classification System, 19.7% of MMC were in class 1, 6.6% in class 2, and 3.5% in class 3. Univariate analysis of MMC participants demonstrated demographic (age, sex, race/ethnicity, and clinic region) and clinical variables (functional level of lesion, ambulation, and number of shunt surgeries) were associated with OW/OB. The GEE model showed that OW/OB was independently, and significantly, associated with age, sex, race/ethnicity, lesion levels, and geographic location of the clinics.
  
  CONCLUSIONS:
  
  The demographic and clinical factors associated with OW/OB in children and adolescents with SB further our understanding of factors contributing to the higher prevalence of OW/OB in this population and may inform OW/OB prevention and treatment strategies.
  
  
• Subjects:
  Adolescent Child Female Humans Male Meningomyelocele Obesity Overweight Registries Spinal Dysraphism
• Source:
  Pediatrics. 150(6)
• Pubmed ID:
  36416007
• Pubmed Central ID:
  PMC11037268
• Document Type:
  Journal Article
• Funding:
  U01DD001080/ACL/ACL HHSUnited States/ ; U01DD001072/ACL/ACL HHSUnited States/ ; U01 DD001069/DD/NCBDD CDC HHSUnited States/ ; U01 DD001078/DD/NCBDD CDC HHSUnited States/ ; U01DD001093/ACL/ACL HHSUnited States/ ; U01 DD001240/DD/NCBDD CDC HHSUnited States/ ; U01 DD000736/DD/NCBDD CDC HHSUnited States/ ; U01DD001073/ACL/ACL HHSUnited States/ ; U01 DD001080/DD/NCBDD CDC HHSUnited States/ ; U01DD001063/ACL/ACL HHSUnited States/ ; U01DD001074/ACL/ACL HHSUnited States/ ; U01DD001057/ACL/ACL HHSUnited States/ ; U01 DD000738/DD/NCBDD CDC HHSUnited States/ ; U01DD001065/ACL/ACL HHSUnited States/ ; U01 DD001074/DD/NCBDD CDC HHSUnited States/ ; U01 DD001082/DD/NCBDD CDC HHSUnited States/ ; U01 DD001093/DD/NCBDD CDC HHSUnited States/ ; U01 DD001071/DD/NCBDD CDC HHSUnited States/ ; U01 DD001063/DD/NCBDD CDC HHSUnited States/ ; U01 DD000740/DD/NCBDD CDC HHSUnited States/ ; U01 DD001073/DD/NCBDD CDC HHSUnited States/ ; U01DD001071/ACL/ACL HHSUnited States/ ; U01DD001062/ACL/ACL HHSUnited States/ ; U01DD001082/ACL/ACL HHSUnited States/ ; U01 DD001057/DD/NCBDD CDC HHSUnited States/ ; U01 DD000774/DD/NCBDD CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ ; U01 DD001072/DD/NCBDD CDC HHSUnited States/ ; U01 DD001062/DD/NCBDD CDC HHSUnited States/ ; U01DD001078/ACL/ACL HHSUnited States/ ; U01DD001069/ACL/ACL HHSUnited States/ ; U01 DD000766/DD/NCBDD CDC HHSUnited States/ ; U01 DD001065/DD/NCBDD CDC HHSUnited States/ ; U01 DD001091/DD/NCBDD CDC HHSUnited States/ ; U01DD001091/ACL/ACL HHSUnited States/ ; U01 DD000743/DD/NCBDD CDC HHSUnited States/
• Volume:
  150
• Issue:
  6
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:bf54487f31ef7b9dba4cfb20f6ad36ead9072d551813672f567c9803800d8366
• Download URL:
  https://stacks.cdc.gov/view/cdc/154829/cdc_154829_DS1.pdf
• File Type:
  [PDF - 562.04 KB ]