Rapid increase in the prevalence of metronidazole-resistant Helicobacter pylori in the Netherlands.

van der Wouden, E. J.; van Zwet, A. A.; Vosmaer, G. D.; Oom, J. A.; de Jong, A.; Kleibeuker, J. H.

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Rapid increase in the prevalence of metronidazole-resistant Helicobacter pylori in the Netherlands.

1997 Jul-Sep
By van der Wouden, E. J. ; van Zwet, A. A. ; Vosmaer, G. D. ; ...
Source: Emerg Infect Dis. 3(3):385-389.

[PDF-26.89 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

van der Wouden, E. J. ; van Zwet, A. A. ; Vosmaer, G. D. ; Oom, J. A. ; de Jong, A. ; ... More +

van der Wouden, E. J. ; van Zwet, A. A. ; Vosmaer, G. D. ; Oom, J. A. ; de Jong, A. ; Kleibeuker, J. H. Less -
Description:

The prevalence of primary metronidazole resistance of Helicobacter pylori was studied in one Dutch hospital from 1993 to 1996 and in two additional Dutch hospitals in 1993 and 1996. All cultures of antral biopsy specimens yielding H. pylori in the study period were evaluated, except those from patients who had received anti-H. pylori treatment; 1,037 H. pylori strains, all from different patients were included. Metronidazole resistance was determined by disk diffusion in 1993 and by Epilipsometer-test in 1994 to 1996. Metronidazole resistance increased from 7% (18/245) in 1993 to 32% (161/509) in 1996. More patients with nonulcer dyspepsia and more non-Western European patients were seen in 1996 than in 1993, but age and sex differences were not observed. A comparable increase in metronidazole resistance was observed in both nonulcer dyspepsia patients and peptic ulcer patients, and the prevalence of metronidazole resistance in Western Europeans increased from 5% in 1993 to 28% in 1996.
Subjects:

[+]

Anti-Bacterial Agents Drug Resistance, Microbial Female Helicobacter Infections Helicobacter Pylori Humans Male Metronidazole Peptic Ulcer
Source:

Emerg Infect Dis. 3(3):385-389.
Document Type:

Journal Article
Place as Subject:

Netherlands
Location:

Europe
Volume:

3
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:3fa960514c599c267e3e6a56649b81684747e28a757f23fc59b3d654a8db65c2
Download URL:

https://stacks.cdc.gov/view/cdc/15417/cdc_15417_DS1.pdf
File Type:

	9284388.nxml	txt
	license.txt	txt

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