Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Thomson, K. S. ;
Description:
Many clinical laboratories have problems detecting extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated AmpC beta-lactamases. Confusion exists about the importance of these resistance mechanisms, optimal test methods, and appropriate reporting conventions. Failure to detect these enzymes has contributed to their uncontrolled spread and sometimes to therapeutic failures. Although National Committee for Clinical Laboratory Standards recommendations exist for detecting ESBL- producing isolates of Escherichia coli and Klebsiella spp., no recommendations exist for detecting ESBLs in other organisms or for detecting plasmid-mediated AmpC beta-lactamases in any organisms. Clinical laboratories need to have adequate funding, equipment, and expertise to provide a rapid and clinically relevant antibiotic testing service in centers where these resistance mechanisms are encountered.
Subject:
[+]
Bacterial Proteins
Beta-Lactamases
Clinical Laboratory Techniques
Humans
Plasmids
Research Article

Source:
Emerg Infect Dis. 7(2):333-336. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:d91fa8c972d0903f89c1871f98b114e97511897d78db514afb9a0af6bf5deb09
File Type:

Supporting Files

• 	11294735.nxml	txt
  	license.txt	txt

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