Persistence and variability of Stenotrophomonas maltophilia in cystic fibrosis patients, Madrid, 1991-1998.

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Valdezate, S. ; Vindel, A. ; Maiz, L. ; Baquero, F. ; Escobar, H. ; Cantón, R.
• Description:
  During 1991 to 1998 at least one Stenotrophomonas maltophilia pulmonary infection was observed in 25 (24%) of 104 cystic fibrosis patients at the same unit of our hospital in Spain. Ribotyping and pulse-field gel electrophoresis (PFGE) characterization of 76 S. maltophilia isolates from these patients indicated an overall clonal incidence of 47.1%, reflecting new strains in 44% of patients with repeated positive cultures for S. maltophilia. Six patients with repeated episodes were persistently colonized (> or = 6 months) with the same strain. S. maltophilia bacterial counts were higher (geometric mean, 2.9 x 10(8) cfu/mL) in patients with repeated episodes than in those with a single episode (8.4 x 10(4) cfu/mL, p < 0.01). Single episodes of S. maltophilia occurred in patients < 10 years of age (43% [6/14]), whereas chronic colonization occurred more frequently in older patients (> 16 years of age).
• Subjects:
  Adolescent Adult Child Colony Count, Microbial Cystic Fibrosis Electrophoresis, Gel, Pulsed-Field Female Humans Male Ribotyping Stenotrophomonas Maltophilia Time Factors

  More +
• Source:
  Emerg Infect Dis. 7(1):113-122.
• Document Type:
  Journal Article
• Place as Subject:
  Spain
• Location:
  Europe
• Volume:
  7
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:33ad1e048577588d0eb5b3165926cac5a8d2d005e67c2d4b5c6c17bf697ce12a
• Download URL:
  https://stacks.cdc.gov/view/cdc/15067/cdc_15067_DS1.pdf
• File Type:
  [PDF - 140.10 KB ]