Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance mechanisms and trends in human isolates.

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Engberg, J. ; Aarestrup, F. M. ; Taylor, D. E. ; Gerner-Smidt, P. ; Nachamkin, I.
• Description:
  The incidence of human Campylobacter jejuni and C. coli infections has increased markedly in many parts of the world in the last decade as has the number of quinolone-resistant and, to a lesser extent, macrolide-resistant Campylobacter strains causing infections. We review macrolide and quinolone resistance in Campylobacter and track resistance trends in human clinical isolates in relation to use of these agents in food animals. Susceptibility data suggest that erythromycin and other macrolides should remain the drugs of choice in most regions, with systematic surveillance and control measures maintained, but fluoroquinolones may now be of limited use in the empiric treatment of Campylobacter infections in many regions.
• Subjects:
  Animal Diseases Animals Anti-Bacterial Agents Anti-Infective Agents Campylobacter Coli Campylobacter Jejuni Drug Resistance, Microbial Drug Resistance, Multiple Fluoroquinolones Humans Macrolides Time Factors

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• Source:
  Emerg Infect Dis. 7(1):24-34.
• Document Type:
  Journal Article
• Volume:
  7
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6c41ced077ec58e15944a40829259cb0b711db82e91f625dc538813ad5ddd1ee
• Download URL:
  https://stacks.cdc.gov/view/cdc/15059/cdc_15059_DS1.pdf
• File Type:
  [PDF - 105.78 KB ]