Sin nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome.

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Bostik, P. ; Winter, J. ; Ksiazek, T. G. ; Rollin, P. E. ; Villinger, F. ; Zaki, S. R. ; Peters, C. J. ; Ansari, A. A.
• Description:
  Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).
• Subjects:
  Acute Disease Antibodies, Viral Antigens, Viral Chronic Disease Hantavirus Hantavirus Pulmonary Syndrome Humans Immunoglobulin A Immunoglobulin G Immunoglobulin Isotypes Immunoglobulin M Prognosis

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• Source:
  Emerg Infect Dis. 6(2):184-187.
• Document Type:
  Journal Article
• Volume:
  6
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:87c28b88a44a05b95d56f129feee00552bdf9255ebfa25e622200e247b113bb3
• Download URL:
  https://stacks.cdc.gov/view/cdc/14965/cdc_14965_DS1.pdf
• File Type:
  [PDF - 175.76 KB ]