Sin Nombre Virus (SNV) Ig Isotype Antibody Response During Acute and Convalescent Phases of Hantavirus Pulmonary Syndrome

Details

• Journal Article:
  Emerging Infectious Diseases
• Personal Author:
  Bostik, P. ; Winter, J. ; Ksiazek, T. G. ; Rollin, P. E. ; Villinger, F. ; Zaki, S. R. ; Peters, C. J. ; Ansari, A. A.
• Description:
  Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).
• Subjects:
  Acute Disease Antibodies, Viral Antigens, Viral Chronic Disease Hantavirus Infections Hantavirus Pulmonary Syndrome Humans Immunoglobulin A Immunoglobulin G Immunoglobulin Isotypes Immunoglobulin M Orthohantavirus Prognosis Sin Nombre Virus Zoonoses

  More +
• Series:
  Emerging Infectious Diseases
• DOI:
  https://doi.org/10.3201/eid0602.000213
• ISSN:
  1080-6059 (digital) ; 1080-6040 (print)
• Publisher:
  Centers for Disease Control and Prevention (CDC) (U.S.)
• Pubmed ID:
  10756154
• Pubmed Central ID:
  PMC2640842
• Document Type:
  Text ; Journal Article
• Genre:
  Journal Article
• Rights:
  Public Domain
• Topic:
  Diseases & Conditions
• Volume:
  6
• Issue:
  2
• Citation:
  Emerg Infect Dis. 6(2):184-187.
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha-512:2ac895667e4b734b93c80bc711596a11a9eb70a45b1434dbed997c36e2f970aa5b74584976d50f85675d47f21f5a052eda932881d23b642000b07d4942707604
• Download URL:
  https://stacks.cdc.gov/view/cdc/14965/cdc_14965_DS1.pdf
• File Type:
  [PDF - 175.76 KB ]