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Description:iText is an individual-level, mobile health intervention focusing on improving PrEP adherence. The iText platform utilizes weekly bidirectional short message services (SMS) or email messages to check in with study participants and encourage PrEP adherence. Study participants choose their method of communication (SMS or e-mail), which outgoing message to respond to (i.e., “How are you doing?,” “Are you okay?,” or “How is PrEP going?”) and their response to the question (i.e., “Ok” or “not OK”, “Fine” or “not fine”). If a participant responds with “not OK” or did not respond to the weekly message, a reminder message is sent within 48 hours and a study staff person contacts them by phone. Following the completion of the study at 12 weeks, which was aligned with the participants’ quarterly iPrEx Open Label Extension (OLE) visit, participants completed a follow-up questionnaire and were deactivated from the iText system
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