Nosocomial Infection with Vancomycin-dependent Enterococci1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Tambyah, Paul A. ; Marx, John A. ; Maki, Dennis G.
• Description:
  We report three patients infected with unique strains of vancomycin-dependent enterococci. Two were first infected by genetically identical strains of vancomycin-resistant enterococci (VRE). All three patients had much greater exposure to vancomycin and third-generation cephalosporins than did two control groups (patients infected with VRE and hospitalized patients without enterococcal infections). While antimicrobial pressure promotes nosocomial colonization by VRE, prolonged exposure to vancomycin may foster the transition from vancomycin resistance to dependence.
• Subjects:
  • Research
  • Vancomycin
  • antibiotic use
  • antimicrobial resistance
  • Enterococcus
  • nutritionally deficient microorganisms
  • vancomycin-resistant enterococci (VRE)
  • vancomycin-dependent enterococci (VDE)
  • dispatch
  • Anti-Bacterial Agents
  More +
• Source:
  Emerg Infect Dis. 10(7):1277-1281.
• Document Type:
  Journal Article
• Volume:
  10
• Issue:
  7
• Download URL:
  https://stacks.cdc.gov/view/cdc/14545/cdc_14545_DS1.pdf
• File Type:
  [PDF - 208.84 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b5f60bbab50256a69d25c71fe108178d06db8b8eaeecd5a7fd9fe91296a16ea6