Space-Time Cluster Analysis of Invasive Meningococcal Disease

Hoebe, Christian J.P.A.; de Melker, Hester; Spanjaard, Lodewijk; Dankert, Jacob; Nagelkerke, Nico

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Space-Time Cluster Analysis of Invasive Meningococcal Disease

Published Date:

Sep 2004

Source:

Emerg Infect Dis. 10(9):1621-1626.

[PDF-98.20 KB]

Details:

Personal Authors:

Hoebe, Christian J.P.A. ; de Melker, Hester ; Spanjaard, Lodewijk ; Dankert, Jacob ; Nagelkerke, Nico ;

Keywords:

[+]

Description:

Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993-2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%-4.1%).

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

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