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Space-Time Cluster Analysis of Invasive Meningococcal Disease
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Published Date:
Sep 2004
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Source:Emerg Infect Dis. 10(9):1621-1626.
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Alternative Title:Emerg Infect Dis
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Description:Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993-2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%-4.1%).
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