Flow Cytometry and T-Cell Response Monitoring after Smallpox Vaccination

Poccia, Fabrizio; Gioia, Cristiana; Montesano, Carla; Martini, Federico; Horejsh, Douglas; Castilletti, Concetta; Pucillo, Leopoldo Paolo; Capobianchi, Maria Rosaria; Ippolito, Giuseppe

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Flow Cytometry and T-Cell Response Monitoring after Smallpox Vaccination

Published Date:

Nov 2003

Source:

Emerg Infect Dis. 9(11):1468-1470.

[PDF - 156.02 KB]

Details:

Personal Authors:

Poccia, Fabrizio ; Gioia, Cristiana ; Montesano, Carla ; Martini, Federico ; Horejsh, Douglas ; ... More ▼

Keywords:

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Description:

Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox. When the high similarity between the orthopoxviruses is considered, this rapid assay that uses vaccinia antigens could identify recently exposures.

Supporting Files:

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