Flow Cytometry and T-Cell Response Monitoring after Smallpox Vaccination

Poccia, Fabrizio; Gioia, Cristiana; Montesano, Carla; Martini, Federico; Horejsh, Douglas; Castilletti, Concetta; Pucillo, Leopoldo Paolo; Capobianchi, Maria Rosaria; Ippolito, Giuseppe

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Flow Cytometry and T-Cell Response Monitoring after Smallpox Vaccination

Published Date:

Nov 2003

Source:

Emerg Infect Dis. 9(11):1468-1470.

[PDF-156.02 KB]

Details:

Personal Authors:

Poccia, Fabrizio ; Gioia, Cristiana ; Montesano, Carla ; Martini, Federico ; Horejsh, Douglas ; ... More ▼

Keywords:

[+]

Description:

Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox. When the high similarity between the orthopoxviruses is considered, this rapid assay that uses vaccinia antigens could identify recently exposures.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

	03-0349-F.gif	image/gif
	03-0349-F.jpg	image/jpeg
	03-0349.nxml	text/plain
	license.txt	text/plain

No Related Documents.

You May Also Like:

Antibody Inhibition of a Viral Type 1 Interferon Decoy Receptor Cures a Viral Disease by Restoring Interferon Signaling in the Liver

Personal Author:

Xu, Ren-Huan; Rubio, Daniel; Roscoe, Felicia; Krouse, Tracy E.; Truckenmiller, Mary Ellen; Norbury, Christopher C.; Hudson, Paul N.; Damon, Inger K.; Alcamí, Antonio; Sigal, Luis J.;

Published:

Jan 05 2012

Source:

PLoS Pathog. 2012; 8(1).

Description:

Type 1 interferons (T1-IFNs) play a major role in antiviral defense, but when or how they protect during infections that spread through the lympho-hematogenous route is not known. Orthopoxviruses, including those that produce smallpox and mousepox, s...

File Type:

[PDF - 1.84 MB]
Non-neutralizing antibodies induced by seasonal influenza vaccine prevent, not exacerbate A(H1N1)pdm09 disease

Personal Author:

Kim, Jin Hyang; Reber, Adrian J.; Kumar, Amrita; Ramos, Patricia; Sica, Gabriel; Music, Nedzad; Guo, Zhu; Mishina, Margarita; Stevens, James; York, Ian A.; Jacob, Joshy; Sambhara, Suryaprakash;

Published:

Nov 16 2016

Source:

Sci Rep. 2016; 6.

Description:

The association of seasonal trivalent influenza vaccine (TIV) with increased infection by 2009 pandemic H1N1 (A(H1N1)pdm09) virus, initially observed in Canada, has elicited numerous investigations on the possibility of vaccine-associated enhanced di...

File Type:

[PDF - 1.76 MB]
Guidelines for performing single-platform absolute CD4+ T-cell determinations with CD45 gating for persons infected with human immunodeficiency virus; Guidelines for using the quantiFERON-TB test for diagnosing latent Mycobacterium tuberculosis infection

Personal Author:

Mazurek, Gerald H.; McDougal, J. Steven; Nicholson, Janet K. A., 1948-; Villarino, Margarita E.;

Corporate Author:

National Center for HIV, STD, and TB Prevention (U.S.), Division of Tuberculosis Elimination.. Centers for Disease Control and Preventiom (U.S.). National Center for Infectious Diseases (U.S.). National Center for Infectious Diseases (U.S.), Division of AIDS, STD, and TB Laboratory Research..

Published:

January 31, 2003

Series:

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 52, no. RR-2

Description:

These guidelines were developed by CDC for laboratorians who perform immunophenotyping for detection and enumeration of CD4+ T-cells and other lymphocyte subsets in persons infected with human immunodeficiency virus (HIV). The guidelines describe sin...

Status:

current

File Type:

[PDF - 397.78 KB]
Guidelines for Using the QuantiFERON-TB Test for Diagnosing Latent Mycobacterium Tuberculosis Infection. Centers for Disease Control and Prevention

Corporate Author:

National Center for HIV, STD, and TB Prevention (U.S.). Division of Tuberculosis Elimination.

Published:

January 31, 2003

Source:

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. 2003; 52(RR-2):15-8.

Description:

This statement provides new recommendations for targeted tuberculin testing and treatment regimens for persons with latent tuberculosis infection (LTBI) and updates previously published guidelines (1,2). This statement is issued in recognition of the...

Status:

superseded

File Type:

[PDF - 397.78 KB]
T Cell Chemo-Vaccination Effects after Repeated Mucosal SHIV Exposures and Oral Pre-Exposure Prophylaxis

Personal Author:

Kersh, Ellen N.; Adams, Debra R.; Youngpairoj, Ae S.; Luo, Wei.; Zheng, Qi.; Cong, Mian-er.; Aung, Wutyi.; Mitchell, James.; Otten, Ron.; Hendry, R. Michael.; Heneine, Walid.; McNicholl, Janet.; Garcia-Lerma, J. Gerardo.;

Published:

Apr 26 2011

Source:

PLoS One. 6(4).

Description:

Pre-exposure prophylaxis (PrEP) with anti-viral drugs is currently in clinical trials for the prevention of HIV infection. Induction of adaptive immune responses to virus exposures during anti-viral drug administration, i.e., a "chemo-vaccination" ef...

File Type:

[PDF - 1.14 MB]