Hospital-reported Pneumococcal Susceptibility to Penicillin1

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Metlay, Joshua P. ; Branas, Charles C. ; Fishman, Neil O.
• Description:
  Geographic variation in drug susceptibility among isolates of Streptococcus pneumoniae has influenced national treatment guidelines for community-acquired pneumonia. Whether individual hospital susceptibility data provide reliable and valid information for providers is unclear. We examined the geographic and temporal variability in hospital-reported rates of pneumococcal susceptibility. We surveyed all 52 hospitals that provided acute adult care in the five counties surrounding Philadelphia and collected data on levels of penicillin susceptibility among all pneumococcal blood isolates from 1998 to 2000. In 1998, pneumococcal nonsusceptibility to penicillin varied from 0% to 67% of all blood isolates across the 33 hospitals with >10 isolates in that year. Hospital location did not correlate with the level of reported pneumococcal susceptibility (p = 0.8). In addition, correlations were not significant in reported pneumococcal susceptibility to penicillin within individual hospitals during the 3 years.
• Subjects:
  Adult Community-Acquired Infections Cross-Sectional Studies Humans Laboratories, Hospital Penicillins Pneumonia, Pneumococcal Streptococcus Pneumoniae
• Source:
  Emerg Infect Dis. 10(1):54-59.
• Document Type:
  Journal Article
• Funding:
  R01-AI46645/AI/NIAID NIH HHS/United States
• Place as Subject:
  Pennsylvania
• Volume:
  10
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:dc3d301bef6423b13733af317b7116aaab8c03e71654e25483a848bd775e81a4
• Download URL:
  https://stacks.cdc.gov/view/cdc/14273/cdc_14273_DS1.pdf
• File Type:
  [PDF - 84.41 KB ]