Tick-Borne Encephalitis with Hemorrhagic Syndrome, Novosibirsk Region, Russia, 1999
Published Date:Jun 2003
Source:Emerg Infect Dis. 9(6):743-746.
Keywords:Amino Acid Sequence
Encephalitis Viruses, Tick-Borne
Hemorrhagic Fevers, Viral
Molecular Sequence Data
Description:Eight fatal cases of tick-borne encephalitis with an unusual hemorrhagic syndrome were identified in 1999 in the Novosibirsk Region, Russia. To study these strains, we sequenced cDNA fragments of protein E gene from six archival formalin-fixed brain samples. Phylogenetic analysis showed tick-borne encephalitis variants clustered with a Far Eastern subtype (homology 94.7%) but not with the Siberian subtype (82%).
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