Cowpox with Severe Generalized Eruption, Finland

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Pelkonen, Paula M. ; Tarvainen, Kyllikki ; Hynninen, Arja ; Kallio, Eva R.K. ; Henttonen, Heikki ; Palva, Airi ; Vaheri, Antti ; Vapalahti, Olli
• Description:
  Cowpox with a severe, generalized eruption was diagnosed in an atopic 4-year-old girl by electron microscopy, virus isolation, polymerase chain reaction, and immunoglobulin (Ig) M and low-avidity IgG antibodies. The hemagglutinin gene of the isolate clustered with a Russian cowpox virus strain, and more distantly, with other cowpox and vaccinia virus strains. The patient's dog had orthopoxvirus-specific antibodies, indicating a possible transmission route. In Finnish wild rodents, orthopoxvirus seroprevalences were 0%-92%, in humans the seroprevalence was 100% in the age group >50, decreasing towards younger age groups.
• Subjects:
  Animals Antibodies, Viral Child, Preschool Cowpox Virus Dispatch Female Humans
• Source:
  Emerg Infect Dis. 9(11):1458-1461.
• Document Type:
  Journal Article
• Place as Subject:
  Finland
• Location:
  Europe
• Volume:
  9
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:fd95d630a46c1d8c064d0736e90283f4b6313bc121a1d8066c424335fab1486c
• Download URL:
  https://stacks.cdc.gov/view/cdc/14201/cdc_14201_DS1.pdf
• File Type:
  [PDF - 332.70 KB ]