Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates

Pérez-Trallero, Emilio; Marimon, José M.; Iglesias, Luis; Larruskain, Julián

doi:10.3201/eid0909.020810

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Fluoroquinolone and Macrolide Treatment Failure in Pneumococcal Pneumonia and Selection of Multidrug-Resistant Isolates

Published Date:

Sep 2003

Publisher's site:

http://dx.doi.org/10.3201/eid0909.020810 New Site Icon

Source:

Emerg Infect Dis. 9(9):1159-1162.

[PDF - 307.47 KB]

Details:

Personal Authors:

Pérez-Trallero, Emilio ; Marimon, José M. ; Iglesias, Luis ; Larruskain, Julián ;

Keywords:

[+]

Description:

Streptococcus pneumoniae serotype 3, isolated from a penicillin-allergic patient and initially susceptible to fluoroquinolones, macrolides, lincosamides, quinupristin-dalfopristin, and telithromycin, became resistant to all these drugs during treatment. Mutations in the parC and gyrA and in the 23S rRNA and the ribosomal protein L22 genes were detected in the resistant isolates.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

02-0810.nxml	text/plain
license.txt	text/plain

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