Molecular Typing of Mycobacterium tuberculosis Strains with a Common Two-Band IS6110 Pattern

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Lok, Kerry H. ; Benjamin, William H. ; Kimerling, Michael E. ; Pruitt, Virginia ; Mulcahy, Donna ; Robinson, Nancy ; Keenan, Nancy B. ; Dunlap, Nancy E.
• Description:
  We conducted a program of population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2452 isolates, 1013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided.
• Subjects:
  Bacterial Typing Techniques Dispatch DNA Fingerprinting Drug Resistance, Bacterial Genetic Variation Humans Molecular Epidemiology Mycobacterium Tuberculosis Tuberculosis
• Source:
  Emerg Infect Dis. 8(11):1303-1305.
• Document Type:
  Journal Article
• Place as Subject:
  Alabama
• Location:
  Africa
• Volume:
  8
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:e9603f91f33a09dce04ff18fac403e7070da9bbdd6951c18ec79154a560a5230
• Download URL:
  https://stacks.cdc.gov/view/cdc/14028/cdc_14028_DS1.pdf
• File Type:
  [PDF - 194.80 KB ]