Antimicrobial Resistance in Streptococcus pneumoniae, Taiwan

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hsueh, Po-Ren ; Luh, Kwen-Tay
• Description:
  Taiwan has one of the highest levels of antibiotic-resistant pneumococcus in the world. Pneumococcal isolates not susceptible to penicillin first appeared in Taiwan in 1986; in 1995 an increase in the prevalence of nonsusceptibility to penicillins, extended-spectrum cephalosporins, trimethoprim-sulfamethoxazole, and macrolides as well as multidrug resistance began to be recognized. With the persistence of antibiotic selective pressure, resistance in some antibiotics reached a high plateau (beta-lactam antibiotics) or continued to increase (macrolides), while novel resistance (fluoroquinolones) emerged in the last 3 years. Widespread distribution of some novel resistant 23F and 19F clones (and the international epidemic of 23F clones) contributes further to the rapid increase of resistance. Because Streptococcus pneumoniae is a major pathogen that causes community-acquired lower respiratory tract infections and meningitis in adults and children, antibiotic-resistance in this organism is a serious problem.
• Subjects:
  Antimicrobial Resistance Drug Resistance Humans Microbial Sensitivity Tests Pneumococcal Infections Prevalence Serotyping Streptococcus Pneumoniae Synopsis Taiwan
• Source:
  Emerg Infect Dis. 8(12):1487-1491.
• Document Type:
  Journal Article
• Volume:
  8
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:357113cd022bc1ccc63266f3e40339c83e1c512accc5a4c28059ca472fa14234
• Download URL:
  https://stacks.cdc.gov/view/cdc/13979/cdc_13979_DS1.pdf
• File Type:
  [PDF - 214.90 KB ]