Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Stringer, James R. ; Beard, Charles B. ; Miller, Robert F. ; Wakefield, Ann E.
Stringer, James R. ; Beard, Charles B. ; Miller, Robert F. ; Wakefield, Ann E. Less -
Description:
The disease known as Pneumocystis carinii pneumonia (PCP) is a major cause of illness and death in persons with impaired immune systems. While the genus Pneumocystis has been known to science for nearly a century, understanding of its members remained rudimentary until DNA analysis showed its extensive diversity. Pneumocystis organisms from different host species have very different DNA sequences, indicating multiple species. In recognition of its genetic and functional distinctness, the organism that causes human PCP is now named Pneumocystis jiroveci Frenkel 1999. Changing the organism's name does not preclude the use of the acronym PCP because it can be read "Pneumocystis pneumonia." DNA sequence variation exists among samples of P. jiroveci, a feature that allows reexamination of the relationships between host and pathogen. Instead of lifelong latency, transient colonization may be the rule.
Subjects:
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Acquired Immunodeficiency Syndrome Aids-Related Opportunistic Infections Genotype Humans Perspective Phylogeny Pneumocystis Infections Pneumonia, Pneumocystis Species Specificity Terminology As Topic
Source:
Emerg Infect Dis. 8(9):891-896.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:0fd23524cbb64c39922e479f884d7ee95f7230054aaefb7c94deac93864952e3
Download URL:
https://stacks.cdc.gov/view/cdc/13946/cdc_13946_DS1.pdf
File Type:

Supporting Files

• 	02-0096_FinalP.nxml	txt
  	license.txt	txt

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