Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Casadevall, Arturo
Description:
The potential threat of biological warfare with a specific agent is proportional to the susceptibility of the population to that agent. Preventing disease after exposure to a biological agent is partially a function of the immunity of the exposed individual. The only available countermeasure that can provide immediate immunity against a biological agent is passive antibody. Unlike vaccines, which require time to induce protective immunity and depend on the host's ability to mount an immune response, passive antibody can theoretically confer protection regardless of the immune status of the host. Passive antibody therapy has substantial advantages over antimicrobial agents and other measures for postexposure prophylaxis, including low toxicity and high specific activity. Specific antibodies are active against the major agents of bioterrorism, including anthrax, smallpox, botulinum toxin, tularemia, and plague. This article proposes a biological defense initiative based on developing, producing, and stockpiling specific antibody reagents that can be used to protect the population against biological warfare threats.
Subjects:
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Anthrax Antibodies Antibodies, Monoclonal Antibody Bacillus Anthracis Bacterial Infections Bacterial Toxins Biological Warfare Biological Weapons Bioterrorism Botulinum Brucella Brucellosis Coxiella Burnetii Francisella Tularensis Humans Immune Immunization Immunization, Passive Perspective Plague Q Fever Ricin Smallpox Toxin Tularemia Vaccines Variola Virus Diseases Yersinia
Source:
Emerg Infect Dis. 8(8):833-841.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:47b5a9f416916446c1611a1de094ba7022e020ce0e3366c9ec6a9a41179829b6
Download URL:
https://stacks.cdc.gov/view/cdc/13895/cdc_13895_DS1.pdf
File Type:

Supporting Files

• 	01-0516_FinalP.nxml	txt
  	license.txt	txt

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