Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Casadevall, Arturo
Description:
The potential threat of biological warfare with a specific agent is proportional to the susceptibility of the population to that agent. Preventing disease after exposure to a biological agent is partially a function of the immunity of the exposed individual. The only available countermeasure that can provide immediate immunity against a biological agent is passive antibody. Unlike vaccines, which require time to induce protective immunity and depend on the host's ability to mount an immune response, passive antibody can theoretically confer protection regardless of the immune status of the host. Passive antibody therapy has substantial advantages over antimicrobial agents and other measures for postexposure prophylaxis, including low toxicity and high specific activity. Specific antibodies are active against the major agents of bioterrorism, including anthrax, smallpox, botulinum toxin, tularemia, and plague. This article proposes a biological defense initiative based on developing, producing, and stockpiling specific antibody reagents that can be used to protect the population against biological warfare threats.
Subject:
[+]
Anthrax
Antibodies
Antibodies, Monoclonal
Antibody
Bacillus Anthracis
Bacterial Infections
Bacterial Toxins
Biological Warfare
Biological Weapons
Bioterrorism
Botulinum
Brucella
Brucellosis
Coxiella Burnetii
Francisella Tularensis
Humans
Immune
Immunization
Immunization, Passive
Perspective
Plague
Q Fever
Ricin
Smallpox
Toxin
Tularemia
Vaccines
Variola
Virus Diseases
Yersinia

Source:
Emerg Infect Dis. 8(8):833-841.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:47b5a9f416916446c1611a1de094ba7022e020ce0e3366c9ec6a9a41179829b6
File Type:

Supporting Files

• 	01-0516_FinalP.nxml	txt
  	license.txt	txt

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