Genetic Characterization of Hantaviruses Transmitted by the Korean Field Mouse (Apodemus peninsulae), Far East Russia

Lokugamage, Kumari; Kariwa, Hiroaki; Hayasaka, Daisuke; Cui, Bai Zhong; Iwasaki, Takuya; Lokugamage, Nandadeva; Ivanov, Leonid I.; Volkov, Vladimir I.; Demenev, Vladimir A.; Slonova, Raisa; Kompanets, Galina; Kushnaryova, Tatyana; Kurata, Takeshi; Maeda, Kenji; Araki, Koichi; Mizutani, Tetsuya; Yoshimatsu, Kumiko; Arikawa, Jiro; Takashima, Ikuo

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Genetic Characterization of Hantaviruses Transmitted by the Korean Field Mouse (Apodemus peninsulae), Far East Russia

Supporting Files Public Domain

Aug 2002
By Lokugamage, Kumari ; Kariwa, Hiroaki ; Hayasaka, Daisuke ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Lokugamage, Kumari ; Kariwa, Hiroaki ; Hayasaka, Daisuke ; Cui, Bai Zhong ; Iwasaki, Takuya ; Lokugamage, Nandadeva ; Ivanov, Leonid I. ; Volkov, Vladimir I. ; Demenev, Vladimir A. ; Slonova, Raisa ; Kompanets, Galina ; Kushnaryova, Tatyana ; Kurata, Takeshi ; Maeda, Kenji ; Araki, Koichi ; Mizutani, Tetsuya ; Yoshimatsu, Kumiko ; Arikawa, Jiro ; Takashima, Ikuo
Description:

In an epizootiologic survey of 122 rodents captured in Vladivostok, Russia, antibodies positive for hantavirus were found in Apodemus peninsulae (4/70), A. agrarius (1/39), and Clethrionomys rufocanus (1/8). The hantavirus sequences identified in two seropositive A. peninsulae and two patients with hemorrhagic fever with renal syndrome (HFRS) from the Primorye region of Far East Russia were designated as Solovey and Primorye, respectively. The nucleotide sequences of the Solovey, Primorye, and Amur (obtained through GenBank) sequences were closely related (>92% identity). Solovey and Primorye sequences shared 84% nucleotide identity with the prototype Hantaan 76-118. Phylogenetic analysis also indicated a close relationship between Solovey, Primorye, Amur, and other viruses identified in Russia, China, and Korea. Our findings suggest that the Korean field mouse (A. peninsulae) is the reservoir for a hantavirus that causes HFRS over a vast area of east Asia, including Far East Russia.
Subjects:

Animals Antibodies, Viral Base Sequence Carrier State DNA, Viral Genetic Variation Hantavirus Infections Humans Mice Molecular Sequence Data Phylogeny Research Rna, Viral Sequence Homology, Nucleic Acid
Source:

Emerg Infect Dis. 8(8):768-776.
Document Type:

Journal Article
Place as Subject:

Russia
Location:

Europe
Volume:

8
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:bf8eb0896c042bfc3119db26b0ca7bc1ea6e2b40da7c18641e463f8fbee23f2a
Download URL:

https://stacks.cdc.gov/view/cdc/13884/cdc_13884_DS1.pdf
File Type:

[PDF - 380.99 KB ]

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