First Characterization of a Cluster of VanA-Type Glycopeptide-Resistant Enterococcus faecium, Colombia

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• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Panesso, Diana ; Ospina, Sigifredo ; Robledo, Jaime ; Vela, María Claudia ; Peña, Julieta ; Hernández, Orville ; Reyes, Jinnethe ; Arias, César A.
• Description:
  From August 1998 to October 1999, glycopeptide-resistant enterococci (GRE) were isolated from 23 infected patients at a teaching hospital in Medellín, Colombia. Identification at the species level and by multiplex polymerase chain reaction assay indicated that all isolates were Enterococcus faecium. The isolates were highly resistant to ampicillin, ciprofloxacin, gentamicin, penicillin, streptomycin, teicoplanin, and vancomycin; they were susceptible only to chloramphenicol, linezolid, and nitrofurantoin. Determination of glycopeptide genotype indicated the presence of the vanA gene in all isolates. Molecular typing by pulsed field gel electrophoresis showed that all isolates were closely related. This study is the first molecular characterization of GRE in Colombia.
• Subjects:
  Anti-Bacterial Agents Bacterial Proteins Carbon-Oxygen Ligases Colombia Disease Outbreaks Drug Resistance, Bacterial Electrophoresis, Gel, Pulsed-Field Enterococci Enterococcus Faecium Evolution, Molecular Genotype Glycopeptide-resistant Enterococci Glycopeptides Gram-Positive Bacterial Infections Hospitals, Teaching Humans Microbial Sensitivity Tests Research Resistance Vancomycin

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• Source:
  Emerg Infect Dis. 8(9):961-965.
• Document Type:
  Journal Article
• Volume:
  8
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:84a7f100015288ea9da42e63fba38b7472c9130f0ca2aa7ca9c26197ccf39400
• Download URL:
  https://stacks.cdc.gov/view/cdc/13866/cdc_13866_DS1.pdf
• File Type:
  [PDF - 353.90 KB ]