Biofilm on Ventriculoperitoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis

Davis, Larry E.; Cook, Guy; Costerton, J. William

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Biofilm on Ventriculoperitoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis

Supporting Files Public Domain

Apr 2002
By Davis, Larry E. ; Cook, Guy ; Costerton, J. William

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Davis, Larry E. ; Cook, Guy ; Costerton, J. William
Description:

We describe a case of recurrent coccidioidal meningitis in which a fungal biofilm on the tip of ventriculo-peritoneal shunt tubing was likely responsible for a 4-year persistence of Coccidioides immitis, despite the patient's taking an adequate dosage of fluconazole. Fungal biofilms should be considered as a cause for treatment failure and fungal persistence, especially when artificial prostheses or indwelling catheters are present.
Subjects:

Antifungal Agents Biofilms Coccidioides Coccidioidomycosis Equipment Contamination Fluconazole Humans Male Meningitis, Fungal Middle Aged Research Treatment Failure Ventriculoperitoneal Shunt
Source:

Emerg Infect Dis. 8(4):376-379.
Document Type:

Journal Article
Volume:

8
Issue:

4
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:66268e6cd10f5485f91ae6125bcebfe8923b89c636736a643ce1bb965e340ff2
Download URL:

https://stacks.cdc.gov/view/cdc/13753/cdc_13753_DS1.pdf
File Type:

[PDF - 4.22 MB ]

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