Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Papa, Anna ; Ma, Benjiang ; Kouidou, Sophie ; Tang, Qing ; Hang, Changshou ; ... More +
Papa, Anna ; Ma, Benjiang ; Kouidou, Sophie ; Tang, Qing ; Hang, Changshou ; Antoniadis, Antonis Less -
Description:
We report the genetic characterization of the M RNA segment of Crimean Congo hemorrhagic fever virus (CCHFV). Two CCHFV strains isolated in Xinjiang Province, a region endemic for CCHF in northwestern China, were studied. These strains, designated BA66019 and BA8402, were isolated in 1965 and 1984 from a CCHF patient and Hyalomma ticks, respectively. Viral RNA was extracted from suckling mouse brains infected with these two strains, amplified, and sequenced. The full-length M RNA, consisting of 5.3 kb, was determined for both strains. The coding nucleotide sequences of the two strains differed from each other by 17.5% and from the reference CCHFV strain IbAr10200 by a mean of 22%, suggesting that the genus Nairovirus comprises a group of genetically highly diverse strains.
Subject:
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Amino Acid Sequence Animals Base Sequence Brain Gene Amplification Gene Products, Env Genetic Variation Hemorrhagic Fever, Crimean Hemorrhagic Fever Virus, Crimean-Congo Humans Mice Molecular Weight Phylogeny Polymerase Chain Reaction Protein Precursors Research RNA, Viral Sequence Alignment
Source:
Emerg Infect Dis. 8(1):50-53.
Document Type:
Journal Article
Place as Subject:
China
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:434af102ca347cf7c1fac565edd9b6a6dfafbccb55b08ca5b2495c4c9c28b65e
Download URL:
https://stacks.cdc.gov/view/cdc/13750/cdc_13750_DS1.pdf
File Type:

Supporting Files

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