Genomic Sequencing Surveillance to Identify Respiratory Syncytial Virus Mutations, Arizona, USA

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Holland, LaRinda A. ; Holland, Steven C. ; Smith, Matthew F. ; Leonard, Victoria R. ; Murugan, Vel ; Nordstrom, Lora ; Mulrow, Mary ; Salgado, Raquel ; White, Michael ; Lim, Efrem S.
• Description:
  We conducted surveillance of respiratory syncytial virus (RSV) genomic sequences for 100 RSV-A and 27 RSV-B specimens collected during November 2022-April 2023 in Arizona, USA. We identified mutations within prefusion F-protein antigenic sites in both subtypes. Continued genomic surveillance will be critical to ensure RSV vaccine effectiveness.
• Subjects:
  Antibodies, Neutralizing Antibodies, Viral Humans Mutation Respiratory Syncytial Virus, Human Respiratory Syncytial Virus Infections Viral Fusion Proteins
• Keywords:
  Antigenic Sites Genomic Surveillance Respiratory Infections Respiratory Syncytial Virus RSV Viruses
• Source:
  Emerg Infect Dis. 2023; 29(11):2380-2382
• Pubmed ID:
  37705075
• Pubmed Central ID:
  PMC10617361
• Document Type:
  Journal Article
• Place as Subject:
  Arizona
• Volume:
  29
• Issue:
  11
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:e54b63cb94588812308b45088b242e957d30105187896495c996974086363e08
• Download URL:
  https://stacks.cdc.gov/view/cdc/135977/cdc_135977_DS1.pdf
• File Type:
  [PDF - 633.57 KB ]