Details:

Alternative Title:
J Med Primatol
Publisher's site:
http://dx.doi.org/10.1111/jmp.12586
Personal Author:
Yee, JoAnn L. ; Grant, Richard ; Haertel, Andrew J. ; Allers, Carolina ; Carpenter, Amanda B. ; ... More +
Yee, JoAnn L. ; Grant, Richard ; Haertel, Andrew J. ; Allers, Carolina ; Carpenter, Amanda B. ; Van Rompay, Koen K. A. ; Roberts, Jeffrey A. Less -
Description:
In efforts to increase rigor and reproducibility, the USA National Primate Research Centers (NPRCs) have focused on qualification of reagents, cross-laboratory validations, and proficiency testing for methods to detect infectious agents and accompanying immune responses in nonhuman primates. The pathogen detection working group, comprised of laboratory scientists, colony managers, and leaders from the NPRCs, has championed the effort to produce testing that is reliable and consistent across laboratories. Through multi-year efforts with shared proficiency samples, testing percent agreement has increased from as low as 67.1% for SRV testing in 2010 to 92.1% in 2019. The 2019 average agreement for the four basic SPF agents improved to >96% (86.5% BV, 98.9 SIV, 92.1 SRV, and 97.0 STLV). As new pathogens such as SARS coronavirus type 2 emerge, these steps can now be quickly replicated to develop and implement new assays that ensure rigor, reproducibly, and quality for NHP pathogen detection.
Subject:
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Animals Primates Reference Standards Reproducibility Of Results Simian T-lymphotropic Virus 1 Specific Pathogen-Free Organisms
Source:
J Med Primatol. 51(4):234-245
Pubmed ID:
35426147
Pubmed Central ID:
PMC9851150
Document Type:
Journal Article
Funding:
P51 OD011092/OD/NIH HHSUnited States/ ; U42 OD024282/CD/ODCDC CDC HHSUnited States/ ; U42 OD010990/OD/NIH HHSUnited States/ ; U42 OD011123/OD/NIH HHSUnited States/ ; U42 OD010568/OD/NIH HHSUnited States/ ; ... More +
P51 OD011092/OD/NIH HHSUnited States/ ; U42 OD024282/CD/ODCDC CDC HHSUnited States/ ; U42 OD010990/OD/NIH HHSUnited States/ ; U42 OD011123/OD/NIH HHSUnited States/ ; U42 OD010568/OD/NIH HHSUnited States/ ; P51 OD010425/OD/NIH HHSUnited States/ ; U42 OD024282/OD/NIH HHSUnited States/ ; P51 OD011107/OD/NIH HHSUnited States/ ; P51 OD011092/CD/ODCDC CDC HHSUnited States/ ; P51 OD011104/OD/NIH HHSUnited States/ ; U42 OD010426/OD/NIH HHSUnited States/ Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:b023ed9f0c16533ed12fed2448886a867dd6d8d81c372753cac7e536cf212ac2
Download URL:
https://stacks.cdc.gov/view/cdc/123834/cdc_123834_DS1.pdf
File Type:

Supporting Files

• 	NIHMS1856831-supplement-Supplemental_Table_3b.docx	docx
  	NIHMS1856831-supplement-Supplemental_Table_4a-b.docx	docx
  	nihms-1856831-f0001.gif	gif
  	nihms-1856831-f0001.jpg	jpeg
  	nihms-1856831-f0002.gif	gif
  	nihms-1856831-f0002.jpg	jpeg
  	nihms-1856831.nxml	xml
  	NIHMS1856831-supplement-SupplementalTable_3a.docx	docx
  	NIHMS1856831-supplement-Supplemental_Table_1a-b.docx	docx
  	NIHMS1856831-supplement-Supplemental_Table_2a-b.docx	docx

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