Racial/Ethnic Disparities in Exposure, Disease Susceptibility, and Clinical Outcomes during COVID-19 Pandemic in National Cohort of Adults, United States

Robertson, McKaylee M.; Shamsunder, Meghana G.; Brazier, Ellen; Mantravadi, Mekhala; Zimba, Rebecca; Rane, Madhura S.; Westmoreland, Drew A.; Parcesepe, Angela M.; Maroko, Andrew R.; Kulkarni, Sarah G.; Grov, Christian; Nash, Denis

doi:10.3201/eid2811.220072

i

Racial/Ethnic Disparities in Exposure, Disease Susceptibility, and Clinical Outcomes during COVID-19 Pandemic in National Cohort of Adults, United States

Supporting Files

11 2022
By Robertson, McKaylee M. ; Shamsunder, Meghana G. ; Brazier, Ellen ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Robertson, McKaylee M. ; Shamsunder, Meghana G. ; Brazier, Ellen ; Mantravadi, Mekhala ; Zimba, Rebecca ; Rane, Madhura S. ; Westmoreland, Drew A. ; Parcesepe, Angela M. ; Maroko, Andrew R. ; Kulkarni, Sarah G. ; Grov, Christian ; Nash, Denis
Description:

We examined racial/ethnic disparities for COVID-19 seroconversion and hospitalization within a prospective cohort (n = 6,740) in the United States enrolled in March 2020 and followed-up through October 2021. Potential SARS-CoV-2 exposure, susceptibility to COVID-19 complications, and access to healthcare varied by race/ethnicity. Hispanic and Black non-Hispanic participants had more exposure risk and difficulty with healthcare access than white participants. Participants with more exposure had greater odds of seroconversion. Participants with more susceptibility and more barriers to healthcare had greater odds of hospitalization. Race/ethnicity positively modified the association between susceptibility and hospitalization. Findings might help to explain the disproportionate burden of SARS-CoV-2 infections and complications among Hispanic/Latino/a and Black non-Hispanic persons. Primary and secondary prevention efforts should address disparities in exposure, vaccination, and treatment for COVID-19.
Subjects:

Adult COVID-19 Disease Susceptibility Ethnicity Humans Pandemics Prospective Studies SARS-COV-2 White People
Source:

Emerg Infect Dis. 2022; 28(11):2171-2180
Pubmed ID:

36191624
Pubmed Central ID:

PMC9622253
Document Type:

Journal Article
Funding:

P2C HD050924/HD/NICHD NIH HHSUnited States/ ; UH3 AI133675/AI/NIAID NIH HHSUnited States/
Place as Subject:

United States
Volume:

28
Issue:

11
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:f94f7f99952489e173e9f939908e43fb5a0e6f6c29432b1c352c68bba1b557c9
Download URL:

https://stacks.cdc.gov/view/cdc/122850/cdc_122850_DS1.pdf
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[PDF - 733.88 KB ]

22-0072-Techapp-s1.pdf

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