Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2809.220313
Personal Author:
Hills, Thomas ; Sharpe, Caitlin ; Wong, Thomas ; Cutfield, Tim ; Lee, Arier ; ... More +
Hills, Thomas ; Sharpe, Caitlin ; Wong, Thomas ; Cutfield, Tim ; Lee, Arier ; McBride, Stephen ; Rogers, Matthew ; Soh, May Ching ; Taylor, Amanda ; Taylor, Susan ; Thomas, Mark Less -
Description:
Invasive Haemophilus influenzae infection during pregnancy can cause preterm birth and fetal loss, but the mechanism is unclear. We investigated 54 cases of pregnancy-associated invasive H. influenzae disease in 52 unique pregnancies in the Auckland region of New Zealand during October 1, 2008‒September 30, 2018. Intraamniotic infection was identified in 36 (66.7%) of 54 cases. Outcome data were available for 48 pregnancies. Adverse pregnancy outcomes, defined as fetal loss, preterm birth, or the birth of an infant requiring intensive/special care unit admission, occurred in 45 (93.8%) of 48 (pregnancies. Fetal loss occurred in 17 (35.4%) of 48 pregnancies, before 24 weeks' gestation in 13 cases, and at >24 weeks' gestation in 4 cases. The overall incidence of pregnancy-associated invasive H. influenzae disease was 19.9 cases/100,000 births, which exceeded the reported incidence of pregnancy-associated listeriosis in New Zealand. We also observed higher rates in younger women and women of Māori ethnicity.
Subject:
[+]
Female
Gestational Age
Haemophilus Infections
Humans
Infant, Newborn
Pregnancy
Pregnancy Outcome
Premature Birth

Source:
Emerg Infect Dis. 2022; 28(9):1747-1754
Pubmed ID:
35997306
Pubmed Central ID:
PMC9423897
Document Type:
Journal Article
Place as Subject:
New Zealand
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:e566ede5c185d8a3939ffb694c8ba648b458e46f0c471a186b9fd6b881b6e713
File Type:

Supporting Files

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