Expansion of L452R-Positive SARS-CoV-2 Omicron Variant, Northern Lombardy, Italy

Novazzi, Federica; Baj, Andreina; Genoni, Angelo; Focosi, Daniele; Maggi, Fabrizio

doi:10.3201/eid2806.220210

i

Expansion of L452R-Positive SARS-CoV-2 Omicron Variant, Northern Lombardy, Italy

Supporting Files Public Domain

6 2022
By Novazzi, Federica ; Baj, Andreina ; Genoni, Angelo ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Novazzi, Federica ; Baj, Andreina ; Genoni, Angelo ; Focosi, Daniele ; Maggi, Fabrizio
Description:

We report 25 cases of infection with SARS-CoV-2 Omicron variant containing spike protein L452R mutation in northern Lombardy, Italy. Prevalence of this variant was >30% in this region, compared with <0.5% worldwide. Many laboratories are using previously developed L452R-specific PCRs to discriminate Omicron from Delta mutations, but these tests may be unreliable.
Subjects:

Covid-19 Humans Mutation Sars-Cov-2 Spike Glycoprotein, Coronavirus
Source:

Emerg Infect Dis. 2022; 28(6):1301-1302
Pubmed ID:

35416767
Pubmed Central ID:

PMC9155861
Document Type:

Journal Article
Genre:

Letter
Place as Subject:

Italy
Volume:

28
Issue:

6
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:5697c1e626f9125a5b0ed466202b01e273d176cbd210cb305efcdc899197e2d2
Download URL:

https://stacks.cdc.gov/view/cdc/118193/cdc_118193_DS1.pdf
File Type:

[PDF - 319.55 KB ]

22-0210.nxml

Download xml

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.