Expansion of L452R-Positive SARS-CoV-2 Omicron Variant, Northern Lombardy, Italy

Novazzi, Federica; Baj, Andreina; Genoni, Angelo; Focosi, Daniele; Maggi, Fabrizio

doi:10.3201/eid2806.220210

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Expansion of L452R-Positive SARS-CoV-2 Omicron Variant, Northern Lombardy, Italy

6 2022
By Novazzi, Federica ; Baj, Andreina ; Genoni, Angelo ; ...
http://dx.doi.org/10.3201/eid2806.220210
Source: Emerg Infect Dis. 2022; 28(6):1301-1302

[PDF-319.55 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Novazzi, Federica ; Baj, Andreina ; Genoni, Angelo ; Focosi, Daniele ; Maggi, Fabrizio

Novazzi, Federica ; Baj, Andreina ; Genoni, Angelo ; Focosi, Daniele ; Maggi, Fabrizio Less -
Description:

We report 25 cases of infection with SARS-CoV-2 Omicron variant containing spike protein L452R mutation in northern Lombardy, Italy. Prevalence of this variant was >30% in this region, compared with <0.5% worldwide. Many laboratories are using previously developed L452R-specific PCRs to discriminate Omicron from Delta mutations, but these tests may be unreliable.
Subjects:

[+]

Covid-19 Humans Mutation Sars-Cov-2 Spike Glycoprotein, Coronavirus
Source:

Emerg Infect Dis. 2022; 28(6):1301-1302
Pubmed ID:

35416767
Pubmed Central ID:

PMC9155861
Document Type:

Journal Article
Genre:

Letter
Place as Subject:

Italy
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:5697c1e626f9125a5b0ed466202b01e273d176cbd210cb305efcdc899197e2d2
Download URL:

https://stacks.cdc.gov/view/cdc/118193/cdc_118193_DS1.pdf
File Type:

22-0210.nxml

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