SARS-CoV-2 IgG Levels as Predictors of XBB Variant Neutralization, Israel, 2022­ and 2023

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Lustig, Yaniv ; Canetti, Michal ; Indenbaum, Victoria ; Peretz, Yovel ; Weiss-Ottolenghi, Yael ; Margalit, Ili ; Asraf, Keren ; Levin, Tal ; Zuckerman, Neta ; Tomer, Enosh ; Mandelboim, Michal ; Doolman, Ram ; Barda, Noam ; Regev-Yochay, Gili
• Description:
  Although a vaccine against SARS-CoV-2 Omicron-XBB.1.5 variant is available worldwide and recent infection is protective, the lack of recorded infection data highlights the need to assess variant-specific antibody neutralization levels. We analyzed IgG levels against receptor-binding domain-specific SARS-CoV-2 ancestral strain as a correlate for high neutralizing titers against XBB variants.
• Subjects:
  Adult Aged Antibodies, Neutralizing Antibodies, Viral COVID-19 COVID-19 Vaccines Female Humans Immunoglobulin G Male Middle Aged Neutralization Tests SARS-CoV-2 Spike Glycoprotein, Coronavirus

  More +
• Keywords:
  Antibodies IgG Israel Neutralizing Antibodies Respiratory Infections Vaccine-preventable Diseases Vaccines Viruses XBB Variant
• Source:
  Emerg Infect Dis. 2024; 30(5):1050-1052
• Pubmed ID:
  38666742
• Pubmed Central ID:
  PMC11060444
• Document Type:
  Journal Article
• Genre:
  Research Letter
• Place as Subject:
  Israel
• Volume:
  30
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:3e7669a733100a32acdcc90a4e764aeea36e3fbb42edaa6a9785b6e2280271bd
• Download URL:
  https://stacks.cdc.gov/view/cdc/154881/cdc_154881_DS1.pdf
• File Type:
  [PDF - 702.80 KB ]