Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections

Tober-Lau, Pinkus; Gruell, Henning; Vanshylla, Kanika; Koch, Willi M.; Hillus, David; Schommers, Philipp; Suárez, Isabelle; Suttorp, Norbert; Sander, Leif Erik; Klein, Florian; Kurth, Florian

doi:10.3201/eid2805.220271

i

Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections

Supporting Files Public Domain

5 2022
By Tober-Lau, Pinkus ; Gruell, Henning ; Vanshylla, Kanika ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Tober-Lau, Pinkus ; Gruell, Henning ; Vanshylla, Kanika ; Koch, Willi M. ; Hillus, David ; Schommers, Philipp ; Suárez, Isabelle ; Suttorp, Norbert ; Sander, Leif Erik ; Klein, Florian ; Kurth, Florian
Description:

To determine neutralizing activity against the severe acute respiratory syndrome coronavirus 2 ancestral strain and 4 variants of concern, we tested serum from 30 persons with breakthrough infection after 2-dose vaccination. Cross-variant neutralizing activity was comparable to that after 3-dose vaccination. Shorter intervals between vaccination and breakthrough infection correlated with lower neutralizing titers.
Subjects:

Antibodies, Neutralizing Antibodies, Viral Covid-19 Humans Sars-Cov-2 Vaccination
Source:

Emerg Infect Dis. 2022; 28(5):1050-1052
Pubmed ID:

35259088
Pubmed Central ID:

PMC9045428
Document Type:

Journal Article
Genre:

Letter
Volume:

28
Issue:

5
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:d1ea788dab9a78c6906e068a9e619a5d9acbd50d211264410fa1f271f1473863
Download URL:

https://stacks.cdc.gov/view/cdc/117307/cdc_117307_DS1.pdf
File Type:

[PDF - 781.88 KB ]

File Language:

English

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