HIV incidence and prevalence among adults aged 15–64 years in Rwanda: Results from the Rwanda Population-based HIV Impact Assessment (RPHIA) and District-level Modeling, 2019

Details

• Alternative Title:
  Int J Infect Dis
• Personal Author:
  Nsanzimana, Sabin ; Rwibasira, Gallican Nshogoza ; Malamba, Samuel Sewava ; Musengimana, Gentille ; Kayirangwa, Eugenie ; Jonnalagadda, Sasi ; Rezende, Erika Fazito ; Eaton, Jeffrey W ; Mugisha, Veronicah ; Remera, Eric ; Muhamed, Semakula ; Mulindabigwi, Augustin ; Omolo, Jared ; Weisner, Lubbe ; Moore, Carole ; Patel, Hetal ; Justman, Jessica E
• Description:
  Objectives:
  
  The 2018–2019 Rwanda Population–based HIV Impact Assessment (RPHIA) was conducted to measure national HIV incidence and prevalence. District-level estimates were modeled to inform resources allocation.
  
  Methods:
  
  RPHIA was a nationally representative cross-sectional household survey. Consenting adults were interviewed and tested for HIV using the national diagnostic algorithm followed by laboratory-based confirmation of HIV status and testing for viral load (VL), limiting antigen (LAg) avidity, and presence of antiretrovirals. Incidence was calculated using normalized optical density ≤ 1·5, VL ≥ 1,000 copies/mL, and undetectable antiretrovirals. Survey and programmatic data were used to model district-level HIV incidence and prevalence.
  
  Results:
  
  Of 31,028 eligible adults, 98·7% participated in RPHIA and 934 tested HIV positive. HIV prevalence among adults in Rwanda was 3·0% (95% CI:2·7–3·3). National HIV incidence was 0·08% (95% CI:0·02–0·14) and 0·11% (95% CI:0·00–0·26) in the City of Kigali (CoK). Based on district-level modeling, HIV incidence was greatest in the 3 CoK districts (0·11% to 0·15%) and varied across other districts (0·03% to 0·10%).
  
  Conclusions:
  
  HIV prevalence among adults in Rwanda is 3.0%; HIV incidence is low at 0.08%. District-level modeling has identified disproportionately affected urban hotspots: areas to focus resources.
  
  
• Subjects:
  Adolescent Adult Article Cross-Sectional Studies HIV HIV Infections Humans Incidence Middle Aged Naomi Model Population-based Surveys Prevalence Rwanda Young Adult

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• Source:
  Int J Infect Dis. 116:245-254
• Pubmed ID:
  35066161
• Pubmed Central ID:
  PMC9069967
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; U2G GH001226/GH/CGH CDC HHSUnited States/
• Volume:
  116
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:659ff55e4a666c0d1d3fb87c8017ad552ba3d25b86e3bb04e7d9f41f5db51a39
• Download URL:
  https://stacks.cdc.gov/view/cdc/117065/cdc_117065_DS1.pdf
• File Type:
  [PDF - 1.68 MB ]