Details:

Alternative Title:
Occup Environ Med
Publisher's site:
http://dx.doi.org/10.1136/oemed-2021-107561
Personal Author:
Siegel, Miriam R. ; Rocheleau, Carissa M. ; Broadwater, Kendra ; Santiago-Colón, Albeliz ; Johnson, Candice Y. ; ... More +
Siegel, Miriam R. ; Rocheleau, Carissa M. ; Broadwater, Kendra ; Santiago-Colón, Albeliz ; Johnson, Candice Y. ; Herdt, Michele L. ; Chen, I-Chen ; Lawson, Christina C. Less -
Corporate Authors:
National Birth Defects Prevention Study
Description:
Objective:

Nail technicians and hairdressers may be exposed to chemicals with potential reproductive effects. While studies have examined birth defects in children of hairdressers, nail technicians have not been evaluated. We investigated associations between selected birth defects and maternal occupation as a nail technician or hairdresser versus a non-cosmetology occupation during pregnancy.

Methods:

We analyzed population-based case-control data from the multisite National Birth Defects Prevention Study, 1997–2011. Cases were fetuses or infants with major structural birth defects; controls were liveborn infants without major birth defects. Expert raters classified self-reported maternal jobs as either nail technician, combination nail technician-hairdressing, hairdressing, other cosmetology, or non-cosmetology work. We used logistic regression to calculate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for associations between occupation during pregnancy and birth defects, controlling for age, smoking, education, and race/ethnicity.

Results:

Sixty-one mothers worked as nail technicians, 196 as hairdressers, 39 as combination nail technician-hairdressers, and 42,810 as non-cosmetologists. The strongest associations among nail technicians included seven congenital heart defect (CHD) groups (ORs ranging from 2.7 to 3.5) and neural tube defects (OR=2.6, CI: 0.8–8.4). Birth defects most strongly associated with hairdressing included anotia/microtia (OR=2.1; CI: 0.6–6.9) and cleft lip with cleft palate (OR=2.0; CI: 1.1–3.7). All oral cleft groups were associated with combination nail technician-hairdresser work (ORs ranging from 4.2 to 5.3).

Conclusions:

Small samples resulted in wide confidence intervals. Still, results suggest associations between maternal nail technician work during pregnancy and CHDs and between hairdressing work and oral clefts.


Subjects:
[+]
Adult Barbering Beauty Culture Case-Control Studies Cleft Lip Cleft Palate Congenital Abnormalities Congenital Microtia Female Heart Defects, Congenital Humans Maternal Exposure Neural Tube Defects Occupational Exposure Pregnancy Pregnant Women
Source:
Occup Environ Med. 79(1):17-23
Pubmed ID:
34193593
Pubmed Central ID:
PMC8991319
Document Type:
Journal Article
Funding:
CC999999/ImCDC/Intramural CDC HHSUnited States/
Name as Subject:
National Birth Defects Prevention Study (U.S.)
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:3a6fcd2d3e52ecb731b9831d8a874b797bf153f74af20a28cf97dd1dea1f2f46
Download URL:
https://stacks.cdc.gov/view/cdc/116102/cdc_116102_DS1.pdf
File Type:

Supporting Files

• nihms-1792047.nxml

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