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Cancer Specific Survival in Patients with Sickle Cell Disease
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4 2019
Source: Br J Haematol. 185(1):128-132 -
Alternative Title:Br J Haematol
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Description:Sickle cell disease (SCD) patients have a higher incidence of certain cancers, but no studies have determined the impact of cancer on survival among SCD patients. SCD patients (n = 6423), identified from state-wide hospitalisation data, were linked to the California Cancer Registry (1988-2014). Multivariable Cox proportional hazards regression was used to examine survival. Among SCD patients, a cancer diagnosis was associated with a 3-fold increased hazard of death. Compared to matched cancer patients without SCD, SCD was associated with worse overall survival, but not cancer-specific survival, suggesting that SCD cancer patients should be treated with similar therapeutic intent.
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Pubmed ID:30467842
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Pubmed Central ID:PMC8966490
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